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12602

Sigma-Aldrich

Potassium bicarbonate

puriss., meets analytical specification of Ph. Eur., BP, USP, E501, 99.5-101.0% (acidimetric)

Synonym(s):

Potassium hydrogen carbonate

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About This Item

Linear Formula:
KHCO3
CAS Number:
Molecular Weight:
100.12
Beilstein:
4535309
EC Number:
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.21

grade

puriss.

Quality Level

Assay

99.5-101.0% (acidimetric)

form

powder or crystals

quality

meets analytical specification of Ph. Eur., BP, USP, E501

impurities

organic volatile impurities, complies (GC)
≤0.0005% heavy metals (as Pb)
≤0.002% ammonium (NH4)

loss

≤0.1% loss on drying, 4 h (on silica gel)

pH

8.0-8.6 (20 °C, 5%)

solubility

water: soluble(lit.)

anion traces

carbonate (K2CO3): ≤2.5%
chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤100 mg/kg

cation traces

As: ≤1 mg/kg
Ca: ≤50 mg/kg
Fe: ≤10 mg/kg
Na: ≤300 mg/kg
Pb: ≤5 mg/kg

suitability

complies for appearance of solution

SMILES string

[K+].OC([O-])=O

InChI

1S/CH2O3.K/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1

InChI key

TYJJADVDDVDEDZ-UHFFFAOYSA-M

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General description

Potassium bicarbonate (Potassium hydrogen carbonate) is an inexpensive, nontoxic base. It is used to regulate pH or as a reagent.

Application

Potassium bicarbonate is used:
  • In the synthesis of cyclic ammonium cation N,N-dimethyl-3,5-dimethylpiperidinium (DMDMP).
  • As a base in the preparation of glycerol carbonate and glycidol from 3-chloro-1,2-propanediol (HAL).

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Relation between phosphate energy donors and incorporation of labeled amino acids into proteins.
P C ZAMECNIK et al.
The Journal of biological chemistry, 209(1), 337-354 (1954-07-01)
Constance Alabert et al.
Cell reports, 30(4), 1223-1234 (2020-01-30)
Chromatin states must be maintained during cell proliferation to uphold cellular identity and genome integrity. Inheritance of histone modifications is central in this process. However, the histone modification landscape is challenged by incorporation of new unmodified histones during each cell
Masaru Watanabe et al.
Carbohydrate research, 341(18), 2891-2900 (2006-11-01)
Liquefaction of glucose into oil was examined in hot-compressed water at 300 degrees C and 30 or 60 min in a tumbling batch reactor. The effects of alkali (KHCO(3)), a hydrogenating agent (HCO(2)H), and a cobalt catalyst (Co(3)O(4)) were studied.
Bess Dawson-Hughes et al.
The Journal of clinical endocrinology and metabolism, 94(1), 96-102 (2008-10-23)
Bicarbonate has been implicated in bone health in older subjects on acid-producing diets in short-term studies. The objective of this study was to determine the effects of potassium bicarbonate and its components on changes in bone resorption and calcium excretion
Judith Buehlmeier et al.
The Journal of clinical endocrinology and metabolism, 97(12), 4789-4797 (2012-10-03)
High sodium chloride (NaCl) intake can induce low-grade metabolic acidosis (LGMA) and may thus influence bone and protein metabolism. We hypothesized that oral potassium bicarbonate (KHCO(3)) supplementation may compensate for NaCl-induced, LGMA-associated bone resorption and protein losses. Eight healthy male

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