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900610

Sigma-Aldrich

Hydroxyl di-benzophenone (PEG)3 alkyne

Synonym(s):

4-(4-((2-(2-(2-(4-(4-(Prop-2-yn-1-yloxy)benzoyl)phenoxy)ethoxy)ethoxy)ethyl)carbamoyl)benzoyl)benzoic acid, Probe building block

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About This Item

Empirical Formula (Hill Notation):
C37H33NO9
Molecular Weight:
635.66
UNSPSC Code:
12352200
NACRES:
NA.22

form

powder or crystals

Quality Level

100

reaction suitability

reaction type: click chemistry

storage temp.

−20°C

Application

Hydroxyl di-benzophenone (PEG)3 alkyne is used for chemical probe synthesis, this trifunctional building block contains two light-activated benzophenones, an alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for dual UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Caution

Light and moisture sensitive(Benzophenone is UV-light activated).

Other Notes

Technology Spotlight: Trifunctional Probe Building Blocks

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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