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Journal of biomedical optics, 14(4), 044019-044019 (2009-09-04)
Coherent anti-Stokes Raman scattering (CARS) microscopy is used to determine the distribution and concentration of selected compounds in intact human hair. By generating images based on ratiometric CARS contrast, quantitative concentration maps of both water and externally applied d-glycine are
Gilthead sea bream (Sparus aurata) is one of the most important farmed Mediterranean fish species, and there is considerable interest for the development of suitable methods to assess its freshness. In the present work, gas chromatography-mass spectrometry-based metabolomics was employed
In the past two decades, metabolomics has proved to be a valuable tool with many potential applications in different areas of science. However, there are still some challenges that need to be addressed, particularly for multicenter studies. These challenges are
Metabolic reprogramming is a hallmark of cancer. Nutrient availability in the tissue microenvironment determines cellular events and may play a role in breast carcinogenesis. High mammographic density is an independent risk factor for breast cancer. Whether nutrient availability differs in
To characterise skin barrier function in vivo at two distinct anatomic sites using minimally invasive bioengineering and biophysical tools. In healthy human volunteers, the quantities of stratum corneum (SC) per unit area of skin on the forearm and forehead were
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