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Key Documents

WH0154214M1

Sigma-Aldrich

Monoclonal Anti-IBRDC1 antibody produced in mouse

clone 4B1, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-C6orf172, Anti-IBR domain containing 1, Anti-MGC26996, Anti-dJ84N20.1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

4B1, monoclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

indirect ELISA: suitable
indirect immunofluorescence: suitable
western blot: 1-5 μg/mL

isotype

IgG2aκ

GenBank accession no.

NM_152553

UniProt accession no.

Q8TC41

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... RNF217(154214)

Related Categories

General description

IBR domain containing 1 (IBRDC1) or ring finger protein 217 is expressed in the skeletal muscle and testis. It is made up of 284 amino acids.

Immunogen

IBRDC1 (NP_689766, 2 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
KVQLGQVEIKCPITECFEFLEETTVVYNLTHEDSIKYKYFLELGRIDSSTKPCPQCKHFTTFKKKGHIPTPSRSESKYKIQCPTCQFVWCFKCHSPWHE

Biochem/physiol Actions

IBR domain containing 1 (IBRDC1) is expressed in leukemia cells. It has been categorized as an E3 ubiquitin-protein ligase.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate buffered saline, pH 7.4

Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Luciana M Fontanari Krause et al.
Scientific reports, 4, 6565-6565 (2014-10-10)
Genomic aberrations involving ETV6 on band 12p13 are amongst the most common chromosomal abnormalities in human leukemia. The translocation t(6;12)(q23;13) in a childhood B-cell acute lymphoblastic leukemia (ALL) cell line fuses ETV6 with the putative long non-coding RNA gene STL.
Jieying Li et al.
Marine biotechnology (New York, N.Y.), 13(2), 232-241 (2010-04-17)
Infectious salmon anemia (ISA) has been described as the hoof and mouth disease of salmon farming. ISA is caused by a lethal and highly communicable virus, which can have a major impact on salmon aquaculture, as demonstrated by an outbreak

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