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SAB1300666

Sigma-Aldrich

Anti-SULT1B1 (C-term) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym(s):

Anti-1B, Anti-Cytosolic, Anti-Member 1, Anti-Sulfotransferase family, Sulfotransferase 1B2

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Pricing and availability is not currently available.

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

indirect ELISA: 1:1000
western blot: 1:100-1:500

NCBI accession no.

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SAB1403200SAB1300669SAB1400269
antibody form

IgG fraction of antiserum

antibody form

ascites fluid

antibody form

IgG fraction of antiserum

antibody form

IgG fraction of antiserum

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

form

buffered aqueous solution

form

-

form

buffered aqueous solution

form

buffered aqueous solution

technique(s)

indirect ELISA: 1:1000, western blot: 1:100-1:500

technique(s)

immunoprecipitation (IP): suitable, indirect ELISA: suitable, western blot: 1-5 μg/mL

technique(s)

indirect ELISA: 1:1000, western blot: 1:100-1:500

technique(s)

western blot: 1 μg/mL

UniProt accession no.

O43704

UniProt accession no.

O43704

UniProt accession no.

O00204

UniProt accession no.

P0DMM9

General description

Sulfotransferases such as SULT1B1 catalyze the biotransformation of a large number of endogenous compounds such as neurotransmitters, steroids, bile acids, and thyroid hormones, as well as drugs and xenobiotics. Fujita et al. (1997) demonstrated that recombinant rat and human SULT1B1, expressed in E. coli, catalyzed sulfation of p-nitrophenol, 3,3-prime,5-triiodothyronine (T3), and dopamine, but not of beta-estradiol and dehydroepiandrosterone. SULT1B1 showed higher affinities for formation of T3 sulfate than did the phenol sulfotransferases ST1A3 (SULT1A1) or ST1A5. Wang et al. (1998) found that bacterially-expressed SULT1B1 sulfated small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3-prime-diiodothyronine, triiodothyronine, reverse triiodothyronine, and thyroxine. No activity was detected against several sterols or dopamine.

Immunogen

SULT1B1 (NP_055280, 268-306)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SULT1B1.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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