Skip to Content
Merck
All Photos(2)

Key Documents

P9879

Sigma-Aldrich

Procaine hydrochloride

≥97% (HPLC), powder, Na⁺ channel blocker

Synonym(s):

4-Aminobenzoic acid 2-diethylaminoethyl ester, p-Aminobenzoic acid diethylaminoethyl ester hydrochloride, Novocaine hydrochloride

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
H2NC6H4CO2CH2CH2N(C2H5)2·HCl
CAS Number:
Molecular Weight:
272.77
Beilstein:
3917802
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

Pricing and availability is not currently available.

product name

Procaine hydrochloride, ≥97%

Quality Level

Assay

≥97%

form

powder

mp

155-156 °C (lit.)

originator

Celgene

SMILES string

Cl.CCN(CC)CCOC(=O)c1ccc(N)cc1

InChI

1S/C13H20N2O2.ClH/c1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3;1H

InChI key

HCBIBCJNVBAKAB-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
Y0000772BP1109PHR1827
manufacturer/tradename

USP

manufacturer/tradename

EDQM

manufacturer/tradename

BP

manufacturer/tradename

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical
pharmaceutical (small molecule)
pharmaceutical small molecule

application(s)

pharmaceutical (small molecule)

format

neat

format

neat

format

neat

format

-

API family

moxidectin

API family

moxidectin

API family

moxidectin

API family

moxidectin

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

-10 to -25°C

Application

Procaine hydrochloride has been used as a component of Krebs Henseleit buffer for incubating the left ventricular cardiac tissue in its resting length.[1] It has also been used as an inducer in M9 media for induction assay.[2]

Biochem/physiol Actions

Procaine is a Na+ channel blocker, commonly used as an anesthetic agent and is considered safer than cocaine.[3] It is also useful as a painkiller to treat pain, associated with joints and tendons.[4]

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by Celgene. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Skin Sens. 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

  • Certificates of Analysis (COA)

    Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Ophthalmic Anaesthesia, 5-5 (2002)
    J Dudel et al.
    Journal of neurophysiology, 81(5), 2386-2397 (1999-05-13)
    of quantal end-plate currents of mouse muscle by physostigmine and procaine. Quantal endplate currents (qEPCs) were recorded from hemidiaphragms of mice by means of a macro-patch-clamp electrode. Excitation was blocked with tetrodotoxin, and quantal release was elicited by depolarizing pulses
    Equine Anesthesia E-Book: Monitoring and Emergency Therapy, 215-215 (2002)
    Cardiac and metabolic changes in long-term high fructose-fat fed rats with severe obesity and extensive intramyocardial lipid accumulation
    Axelsen LN, et al.
    American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 298(6), R1560-R1570 (2010)
    Characterization of combinatorial patterns generated by multiple two-component sensors in E. coli that respond to many stimuli
    Clarke EJ and Voigt CA
    Biotechnology and Bioengineering, 108(3), 666-675 (2011)

    Articles

    Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.

    We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

    We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

    We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

    See All

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service