P3794
Procyclidine hydrochloride
Synonym(s):
α-Cyclohexyl-α-phenyl-1-pyrrolidinepropanol
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About This Item
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form
solid
Quality Level
storage temp.
2-8°C
SMILES string
Cl.OC(CCN1CCCC1)(C2CCCCC2)c3ccccc3
InChI
1S/C19H29NO.ClH/c21-19(17-9-3-1-4-10-17,18-11-5-2-6-12-18)13-16-20-14-7-8-15-20;/h1,3-4,9-10,18,21H,2,5-8,11-16H2;1H
InChI key
ZFSPFXJSEHCTTR-UHFFFAOYSA-N
Gene Information
human ... CHRM1(1128)
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Biochem/physiol Actions
Procyclidine is a synthetic anti-cholinergic agent and atropine-like antispasmodic. It exhibits therapeutic effects against Parkinson′s disease and schizophrenia. Procyclidine acts as a muscarinic receptor antagonist. It also affects N-methyl-D-aspartate (NMDA) glutamine and nicotinic acetylcholine receptors to a lower extent.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Effects of procyclidine on eye movements in schizophrenia
Neuropsychopharmacology, 28(12), 2199-2208 (2003)
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