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GE17549111

HiTrap® MabSelect SuRe pcc

Cytiva 175491111, pkg of 5 × 1 mL

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About This Item

UNSPSC Code:
41106500
NACRES:
NB.21

Pricing and availability is not currently available.

packaging

pkg of 5 × 1 mL

manufacturer/tradename

Cytiva 175491111

bed H × I.D. × volume

(25 mm) (7 mm) (1 mL)

shipped in

ambient

storage temp.

2-8°C

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This Item
GE17549851GE17549112GE17549852
manufacturer/tradename

Cytiva 175491111

manufacturer/tradename

17549851, Cytiva

manufacturer/tradename

Cytiva 17549112

manufacturer/tradename

17549852, Cytiva

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

packaging

pkg of 5 × 1 mL

packaging

pack of 1 × 1 mL

packaging

pack of 1 × 5 mL

packaging

pack of 5 × 1 mL

bed H × I.D. × volume

(25 mm) (7 mm) (1 mL)

bed H × I.D. × volume

-

bed H × I.D. × volume

-

bed H × I.D. × volume

-

General description

HiTrap MabSelect SuRe pcc chromatography columns are prepacked with MabSelect SuRe pcc protein A resin for screening and small-scale mAb purification in continuous bioprocessing using periodic counter-current chromatography (PCC).

  • Convenient prepacked column for fast, reproducible, and easy small-scale purifications.
  • High binding capacity, ~ 60 mg human IgG/mL resin at 2.4 min residence time
  • High productivity through capture of large mass of monoclonal antibodies in a short period of time.
  • Highly concentrated elution pools for operating flexibility and small unit operations.
  • Allows cost-effective cleaning with 0.1–0.5 M NaOH over hundreds of purification cycles.
  • High protein ligand stability reduces ligand leakage.

HiTrap MabSelect SuRe pcc packed columns (1 mL and 5 mL) are suited for small scale antibody purifications, as well as optimization of methods and parameters, such as sample load and protein binding conditions. These protein A columns provide fast, reproducible, and easy separations in a convenient format. The columns are optimally utilized when they are connected to liquid chromatography systems such as the ÄKTA systems.

MabSelect SuRe pcc affinity resin offers exceptional capacity at short residence time, making it well-suited for applications requiring fast mass transfer such as monoclonal antibody capture in a continuous process.

The alkali-stabilized, protein A-derived ligand gives the resin greater stability than conventional protein A-based resins under the alkaline conditions used in cleaning-in-place (CIP) protocols. Consequently, the possibility of cleaning with cost-effective reagents such as sodium hydroxide (NaOH) will improve process economy.

In addition, the use of NaOH for cleaning efficiently inactivates bacteria, mold, and yeast, with improved product quality as a result.

Features and Benefits

  • Convenient prepacked column for Fast, reproducible, and easy small-scale purifications
  • High binding capacity, ~ 60 mg human IgG/mL resin at 2.4 min residence time
  • High productivity through capture of large mass of monoclonal antibodies in a short period of time
  • Highly concentrated elution pools for operating flexibility and small unit operations
  • Allows cost-effective cleaning with 0.1–0.5 M NaOH over hundreds of purification cycles
  • High protein ligand stability reduces ligand leakage

Legal Information

HiTrap is a registered trademark of Cytiva
MabSelect SuRe is a trademark of Cytiva

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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