D9571

Dolasetron mesylate hydrate

≥98% (HPLC), powder

• Synonym(s): Anzemet hydrate, Dolasetron methanesulfonate hydrate
• Empirical Formula (Hill Notation): C₁₉H₂₀N₂O₃ · CH₄O₃S · xH₂O
• CAS Number: 115956-13-3
• Molecular Weight: 420.48 (anhydrous basis)
• UNSPSC Code: 12352200
• PubChem Substance ID: 329798907
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to off-white
• solubility: H₂O: >30 mg/mL
• originator: Sanofi Aventis
• storage temp.: 2-8°C
• SMILES string: O.CS(O)(=O)=O.O=C1CN2[C@@H]3C[C@H](C[C@H]2CC1C3)OC(=O)c4c[nH]c5ccccc45
• InChI: 1S/C19H20N2O3.CH4O3S.H2O/c22-18-10-21-12-5-11(18)6-13(21)8-14(7-12)24-19(23)16-9-20-17-4-2-1-3-15(16)17;1-5(2,3)4;/h1-4,9,11-14,20H,5-8,10H2;1H3,(H,2,3,4);1H2/t11?,12-,13+,14+;;
• InChI key: QTFFGPOXNNGTGZ-BHSFMSKKSA-N

Description

Biochem/physiol Actions

Dolasetron mesylate hydrate is a highly specific and selective serotonin 5-HT3 receptor antagonist, not shown to have activity at other known serotonin receptors and with low affinity for dopamine receptors.

Features and Benefits

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable