D0879
Diisopropylfluorophosphate
Synonym(s):
DFP, DIFP, Diisopropyl phosphorofluoridate, Phosphoric acid diisopropyl ester fluoride
About This Item
Recommended Products
biological source
synthetic (organic)
Quality Level
vapor pressure
0.58 mmHg ( 20 °C)
form
liquid
refractive index
n20/D 1.385 (lit.)
bp
62 °C/9 mmHg (lit.)
mp
−82 °C (lit.)
solubility
anhydrous isopropanol: 0.1-0.5 M (stable for months if stored at -70 °C)
H2O: 1.5% at 25 °C (very unstable (at pH 7.5, half-life = 1 hr); decomposed by alkali.)
density
1.06 g/mL at 25 °C (lit.)
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
Mode of action
protein synthesis | interferes
storage temp.
2-8°C
SMILES string
CC(C)OP(F)(=O)OC(C)C
InChI
1S/C6H14FO3P/c1-5(2)9-11(7,8)10-6(3)4/h5-6H,1-4H3
InChI key
MUCZHBLJLSDCSD-UHFFFAOYSA-N
Gene Information
human ... ACHE(43) , PTGS1(5742) , PTGS2(5743)
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Application
- in combination with inactivated thrombin in Affi-Gel 10 column for the purification of recombinant human thrombomodulin with its chondroitin sulfate chain (shrTMCSA)
- for inducing status epilepticus (SE) in adult rats
- as an irreversible serine protease inhibitor in human neutrophil subcellular fractions
Biochem/physiol Actions
Analysis Note
Other Notes
is unstable when exposed to moisture. DIFP will develop a dark yellow color upon decomposition.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 1 Oral - Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
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