Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

C7519

Sigma-Aldrich

Choline bicarbonate

~80% in H2O

Synonym(s):

2-Hydroxyethyl)trimethylammonium bicarbonate

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
C5H14NO · HCO3
CAS Number:
78-73-9
Molecular Weight:
165.19
MDL number:
MFCD00031689
UNSPSC Code:
50501514
PubChem Substance ID:
24892967
NACRES:
NA.25

form

liquid

Quality Level

200

concentration

~80% in H2O

density

1.17 g/mL at 25 °C (lit.)

lipid type

phospholipids

storage temp.

2-8°C

SMILES string

OC([O-])=O.C[N+](C)(C)CCO

InChI

1S/C5H14NO.CH2O3/c1-6(2,3)4-5-7;2-1(3)4/h7H,4-5H2,1-3H3;(H2,2,3,4)/q+1;/p-1

InChI key

DQKGOGJIOHUEGK-UHFFFAOYSA-M

Looking for similar products? Visit Product Comparison Guide

Application

Choline, a water soluble essential nutrient, is used by the body to make phosphatidylcholine phosphatides and neurotransmitter such as acetylcholine. Choline is used to study a wide range of biological processes from stem cell development to neurological disease studies. Also, An alkaline intermediate useful for preparing salts.

Biochem/physiol Actions

Acyl group acceptor

Substrates

Choline acetyltransferase substrate

Other Notes

Note: The bicarbonate converts to the carbonate with release of CO2 on aging.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Erica C Silva et al.
Research in veterinary science, 135, 42-58 (2021-01-14)
In the present research work, we propose a new antimicrobial treatment for pyoderma via cutaneous permeation of bacteriophage particles conveyed in a hydroxyethylcellulose (HEC) gel integrating ionic liquid as a permeation enhancer. Ionic liquids are highly viscous fluids constituted exclusively
Karen D Corbin et al.
Progress in molecular biology and translational science, 108, 159-177 (2012-06-05)
Advances in nutrigenetics and nutrigenomics have been instrumental in demonstrating that nutrient requirements vary among individuals. This is exemplified by studies of the nutrient choline, in which gender, single-nucleotide polymorphisms, estrogen status, and gut microbiome composition have been shown to
Hussain Mohamad Awwad et al.
Clinical biochemistry, 45(18), 1548-1553 (2012-08-28)
Choline is an essential nutrient that is necessary for cell membrane synthesis and phospholipid metabolism and functions as an important methyl donor. Multiple roles for choline in cancer development have been suggested. Choline can affect DNA methylation and lead to
Mohit J Mehta et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 25(5), 1269-1274 (2018-11-07)
Significant research is currently underway to develop environmentally friendly UV-shielding materials. Herein, we have constructed choline citrate (a biobased ionic liquid, IL) stabilized homogeneous gelatin-lignin UV-shielding films with excellent antimicrobial and mechanical properties. The synthesis procedure of the films is
Vimisha Dharamdasani et al.
Journal of controlled release : official journal of the Controlled Release Society, 323, 475-482 (2020-04-28)
Skin diseases such as lupus, cancer, psoriasis, and hyperhidrosis can potentially be treated effectively by suppressing allele-specific genes using small interfering RNA (siRNA). Injections of siRNA into skin, though effective, are painful and cover small surface areas and thus are
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service