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A6512

Sigma-Aldrich

L-Arginine β-naphthylamide hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C16H21N5O · HCl
CAS Number:
18905-73-2
Molecular Weight:
335.83
EC Number:
242-654-1
MDL number:
MFCD00051283
UNSPSC Code:
12352204
PubChem Substance ID:
24891096
NACRES:
NA.83

Assay

≥98% (TLC)

Quality Level

200

form

powder

solubility

ethanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

storage temp.

−20°C

SMILES string

Cl.N[C@@H](CCCNC(N)=N)C(=O)Nc1ccc2ccccc2c1

InChI

1S/C16H21N5O.ClH/c17-14(6-3-9-20-16(18)19)15(22)21-13-8-7-11-4-1-2-5-12(11)10-13;/h1-2,4-5,7-8,10,14H,3,6,9,17H2,(H,21,22)(H4,18,19,20);1H/t14-;/m0./s1

InChI key

WEVOXPYVEJEKIT-UQKRIMTDSA-N

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H351

Precautionary Statements

P281

Hazard Classifications

Carc. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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H J Ball et al.
Journal of clinical microbiology, 15(1), 28-34 (1982-01-01)
The aminopeptidase activity of arginine-utilizing mycoplasmas was investigated with 20 aminoacyl beta-naphthylamide substrates. High levels of arginyl-beta-naphthylamide hydrolysis were demonstrated in 6 of 11 species when extracts of concentrated washed organisms were used. Relatively low arginine aminopeptidase activity was demonstrated
Yu-Chih Wang et al.
Veterinary microbiology, 142(3-4), 309-312 (2009-11-17)
Enrofloxacin (ER) resistant Actinobacillus pleuropneumoniae strains emerged in Taiwan in 2002. The mechanism of ER resistance in A. pleuropneumoniae has not yet been reported. A total of 48 A. pleuropneumoniae isolates were obtained from the lungs of pigs with pleuropneumonia
Koo-Youn Kim et al.
International journal of food microbiology, 146(1), 52-56 (2011-03-01)
Sixteen Salmonella strains resistant to nalidixic acid isolated from kimbab, the most popular ready-to-eat (RTE) food in Korea, and chicken meat were selected for this study. The resistant strains were shown to have high minimal inhibitory concentrations (MICs) against nalidixic
G Arechaga et al.
Cellular & molecular biology research, 41(5), 369-375 (1995-01-01)
The subcellular distribution of soluble and membrane-bound Arg-beta-naphthylamide-hydrolyzing activities was studied in the left and right rat brain during development and aging. During development, the soluble activity was heterogeneous, whereas adult animals showed the highest activity in the synaptosomal fraction.
Renaud Chollet et al.
Antimicrobial agents and chemotherapy, 48(9), 3621-3624 (2004-08-26)
The role of the AcrAB-TolC pump in macrolide and ketolide susceptibility in Escherichia coli and Enterobacter aerogenes was studied. Efflux pump inhibitor restored erythromycin, clarithromycin, and telithromycin susceptibilities to multidrug-resistant isolates. No modification of telithromycin accumulation was detected in E.
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