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About This Item
Empirical Formula (Hill Notation):
C12H22O11
CAS Number:
Molecular Weight:
342.30
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
EC Number:
225-027-7
Beilstein/REAXYS Number:
93773
MDL number:
Quality Level
assay
≥98.0% (HPLC)
form
solid
optical activity
[α]20/D −48±2°, 24 hr, c = 1% in H2O
color
white to off-white
mp
169 °C ((336 °F ))
storage temp.
room temp
SMILES string
OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO)O[C@@](O)(CO)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O
InChI
1S/C12H22O11/c13-1-4-6(16)7(17)8(18)11(21-4)22-9-5(2-14)23-12(20,3-15)10(9)19/h4-11,13-20H,1-3H2/t4-,5-,6+,7+,8-,9-,10+,11+,12+/m1/s1
InChI key
JCQLYHFGKNRPGE-WJONTELPSA-N
General description
Lactulose is a synthetic derivative of lactose. It is made up of one molecule of galactose and one molecule of fructose.
Application
Lactulose has been used in the preparation of milk.
Lactulose, a disaccharide composed of fructose and galactose units, is used as an osmolyte that relieves constipation and supports probiotic processes in the intestine and colon. Lactulose helps stabilize blood glucose and insulin levels.
Biochem/physiol Actions
Lactulose helps to decrease the concentration of blood ammonia in the treatment of hepatic encephalopathy. It is also used to treat constipation as an osmotic laxative. This non-absorbable disaccharide is catabolized through the bacterial flora to short chain fatty acids. The enzymes of the mammalian digestive tract do not have the ability to digest lactulose.
Other Notes
To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.
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Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Use of lactulose as prebiotic and its influence on the growth, acidification profile and viable counts of different probiotics in fermented skim milk
Oliveira R P D S, et al.
International Journal of Food Microbiology, 145(1), 22-27 (2011)
Gastrointestinal drugs
Small Animal Clinical Pharmacology, 469-497 (2008)
Lactulose enemas in the treatment of hepatic encephalopathy. Do we help or harm?
de Lorenzo-Pinto A, et al.
Revista espa?ola de Enfermedades Digestivas : Organo Oficial de la Sociedad Espa?ola de Patologia Digestiva (2017)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 61360-25G | 04061832700045 |
| 61360-5G | 04061832700052 |