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61354

Sigma-Aldrich

Kollicoat® MAE 100 P

43.2-47.6% methacrylic acid basis (calc. on dried substance)

Synonym(s):

Methacrylic acid-ethyl acrylate copolymer (1:1)

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About This Item

CAS Number:
25212-88-8
UNSPSC Code:
12162002
NACRES:
NA.25

Quality Level

100

Assay

43.2-47.6% methacrylic acid basis (calc. on dried substance)

impurities

≤100 ppm residual monomer (methacrylic acid and ethyl acrylate) (HPLC)
≤20 ppm heavy metals (verified on random samples only)

ign. residue

0.5-3.0% (verified on random samples only)

loss

≤5.0% loss on drying

viscosity

≤100 mPa.s(23 °C) (RV2, 100 PRM, type B)

cation traces

As: ≤2 ppm (verified on random samples only)

InChI

1S/C5H8O2.C4H6O2/c1-3-5(6)7-4-2;1-3(2)4(5)6/h3H,1,4H2,2H3;1H2,2H3,(H,5,6)

InChI key

GDCRSXZBSIRSFR-UHFFFAOYSA-N

Application

Kollicoat MAE can be employed as film coatings (intelligent surfaces). Kollicoat polymers can be used with all standard coating equipment and are cost-effective, delivering maximum quality in terms of function, stability, and appearance. This research grade product is intended for use in R&D and development only.
Kollicoat® MAE 100 P has been used for the production of encapsulated recombinant cytokine (recombinant tumor necrosis factor α).

Analysis Note

solubility: appearance and solubility of a film: clear, soluble in phosphate buffer solution

Legal Information

Kollicoat is a registered trademark of BASF SE

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Wei X, Luo M, Xie Y, et al.
Applied Biochemistry and Biotechnology (2012)
H Kranz et al.
International journal of pharmaceutics, 380(1-2), 112-119 (2009-07-28)
The major aim of this study was to identify an efficient tool to adjust drug release patterns from aqueous and organic ethylcellulose (a gastrointestinal insoluble polymer) coated pellets and to evaluate the long term stability of the film coatings. Drug
J Bajdik et al.
Die Pharmazie, 61(10), 887-888 (2006-10-31)
In the present study the effects of the additives and of storage on the deformation of films prepared from methacrylic acid/ethyl acrylate copolymer with and without polysorbate 80 were evaluated. The films containing polysorbate 80 revealed a longer deformation process
The hygroscopicity of moisture barrier film coatings.
Mwesigwa E, Buckton G, Basit AW.
Drug Devel. Ind. Pharm., 31, 959-968 (2005)

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