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Key Documents

Y0001104

Picosulfate for system suitability

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Sodium picosulfate

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About This Item

Empirical Formula (Hill Notation):
C18H13NNa2O8S2
CAS Number:
10040-45-6
Molecular Weight:
481.41
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

sodium picosulfate

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C18H15NO8S2.2Na/c20-28(21,22)26-15-8-4-13(5-9-15)18(17-3-1-2-12-19-17)14-6-10-16(11-7-14)27-29(23,24)25;;/h1-12,18H,(H,20,21,22)(H,23,24,25);;/q;2*+1/p-2

InChI key

GOZDTZWAMGHLDY-UHFFFAOYSA-L

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Picosulfate for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Douglas K Rex et al.
Gastrointestinal endoscopy, 78(1), 132-141 (2013-04-10)
New bowel cleansers for colonoscopy that lead to improved efficacy, safety, and tolerability are needed. This study evaluated a nonphosphate, dual-action, low-volume, orange-flavored preparation containing sodium picosulfate and magnesium citrate (P/MC). Multicenter, assessor-blinded, randomized, noninferiority study. University hospitals, academic medical
Jennifer A Flemming et al.
Gastrointestinal endoscopy, 75(3), 537-544 (2011-12-24)
Picosulfate, magnesium oxide, and citric acid solution is a small-volume agent for colon cleansing before colonoscopy that is extremely well tolerated by patients, safe, and efficacious. Studies of other cleansing agents have suggested that split-dose regimens may further enhance efficacy.
G Manes et al.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 15(9), 1145-1153 (2013-04-16)
The study compared the efficacy, safety and tolerability of a low-volume picosulphate/magnesium citrate preparation with that of polyethylene glycol plus ascorbic acid (PEG + ASC) in a randomized clinical trial (RCT). A multicentre randomized, single-blinded study was designed. Adult outpatients
HaRyun Won et al.
Obstetrics and gynecology, 121(3), 538-546 (2013-05-03)
Mechanical bowel preparation is a common practice before laparoscopic gynecologic surgery. This study aims to evaluate its capacity to improve surgical view and bowel handling in the deep pelvis. A single-blinded, randomized, controlled trial was undertaken with laparoscopic gynecologic surgical
Magdy El-Salhy et al.
Molecular medicine reports, 7(6), 1757-1760 (2013-04-17)
Endoscopy is an important tool in the diagnosis, follow-up and management of several gastrointestinal diseases. In experimental studies, the course and progression of gastrointestinal lesions are followed by sacrificing animals at specific time intervals and the disease is usually assessed
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