T0500000

Tetracaine hydrochloride

European Pharmacopoeia (EP) Reference Standard

• Synonym(s): 4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester, Amethocaine hydrochloride
• Empirical Formula (Hill Notation): C₁₅H₂₄N₂O₂ · HCl
• CAS Number: 136-47-0
• Molecular Weight: 300.82
• MDL number: MFCD00038912
• UNSPSC Code: 41116107
• PubChem Substance ID: 329826608
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: tetracaine
• manufacturer/tradename: EDQM
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: Cl.CCCCNc1ccc(cc1)C(=O)OCCN(C)C
• InChI: 1S/C15H24N2O2.ClH/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3;/h6-9,16H,4-5,10-12H2,1-3H3;1H
• InChI key: PPWHTZKZQNXVAE-UHFFFAOYSA-N
• Gene Information: human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Topical ophthalmic anesthetic; used for spinal anesthesia

Biochem/physiol Actions

Blocks voltage-sensitive release of Ca²⁺ from sarcoplasmic reticulum.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301,H319,H336
• Precautionary Statements: P261 - P264 - P271 - P280 - P301 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable