Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

D136808

Sigma-Aldrich

2,2-Dimethoxypropane

reagent grade, 98%

Synonym(s):

Acetone dimethyl acetal

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
(CH3)2C(OCH3)2
CAS Number:
77-76-9
Molecular Weight:
104.15
Beilstein:
635678
EC Number:
201-056-0
MDL number:
MFCD00008479
UNSPSC Code:
12352100
PubChem Substance ID:
24893272
NACRES:
NA.21

grade

reagent grade

Quality Level

200

vapor density

3.59 (vs air)

vapor pressure

60 mmHg ( 15.8 °C)

Assay

98%

form

liquid

expl. lim.

31 %, 58 °F
6 %, 27 °F

refractive index

n20/D 1.378 (lit.)

bp

83 °C (lit.)

density

0.847 g/mL at 25 °C (lit.)

SMILES string

COC(C)(C)OC

InChI

1S/C5H12O2/c1-5(2,6-3)7-4/h1-4H3

InChI key

HEWZVZIVELJPQZ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

2,2-Dimethoxypropane (DMP) is an organic building block commonly employed as a precursor to generate 2-methoxypropene (MPP). The degradation study of DMP in ionic liquids showed the formation of MPP and 2-ethoxypropene (EPP) in an identical ratio due to the tunneling effect. Conformational analysis of DMP based on ab initio calculations and matrix isolation infrared spectroscopy has been reported. DMP reacts with water to produce methanol and acetone. This reaction has been employed in a method for the quantification of water in natural products by gas-liquid chromatography. Acidified DMP has been employed for the dehydration of biological samples.

Application

Reagent for the preparation of 1,2-diols as acetonides.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Statements

H225,H319

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Supplementary Hazards

EUH066

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

14.0 °F - closed cup

Flash Point(C)

-10 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
STBL4092
MKCM9898
MKCV5619
STBK4276
STBL3322

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Greene, T.W. Wuts, P.G.M.
Protective Groups in Organic Synthesis, 123-123 (1991)
Davit Jishkariani et al.
ACS nano, 11(8), 7958-7966 (2017-08-05)
Janus nanoparticles (NPs) often referred to as nanosized analogs of molecular surfactants are amphiphilic structures with potential applications in materials science, biomedicine, and catalysis, and their synthesis and self-assembly into complex architectures remain challenging. Here, we demonstrate the preparation of
Gas chromatographic determination of water in natural products by reaction with 2,2-dimethoxypropane.
Mary NY.
Journal of Pharmaceutical Sciences, 58(9), 1089-1092 (1969)
The importance of tunneling effect to the decomposition of 2, 2-dimethoxypropane and 2,2-diethoxypropane.
Jiang H, et al.
Chemical Physics Letters, 406(4), 489-494 (2005)
[Quantitative double-labeled autoradiography by chemical washing method using 2,2-dimethoxypropane].
H Sumiya et al.
Kaku igaku. The Japanese journal of nuclear medicine, 24(3), 315-318 (1987-03-01)
View All Related Papers

Protocols

Derivatization of Fatty acids to FAMEs

Explore how GC can be used to analyze fatty acids either as free fatty acids or as fatty acid methyl esters.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service