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43866

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Salidroside

analytical standard

Synonym(s):

2-(4-Hydroxyphenyl)ethyl β−D-glucopyranoside, p-Hydroxyphenethyl glucopyranoside, Rhodioloside, Rhodosin, Tyrosol a-(β-D-glucopyranoside)

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About This Item

Empirical Formula (Hill Notation):
C14H20O7
CAS Number:
Molecular Weight:
300.30
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥98.0% (HPLC)

optical activity

[α]/D -29±2°, c = 0.5 in methanol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

SMILES string

OC[C@H]1O[C@@H](OCCc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C14H20O7/c15-7-10-11(17)12(18)13(19)14(21-10)20-6-5-8-1-3-9(16)4-2-8/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1

InChI key

ILRCGYURZSFMEG-RKQHYHRCSA-N

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General description

Salidroside is one of the major phenolic glycoside extracted from Rhodiola rosea L(, which can show a broad-spectrum of pharmacological properties like anti-aging, anti-oxidant, anti-cancer and anti-inflammation.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Salidroside, the 8-O-β-D-glucoside of tyrosol, is the main bioactive component of Rhodiola species and is found mainly in the plant roots. It is biosynthesised in the tyrosine metabolism, with glucosylation of tyrosol being the final step. It has been reported to be neuroprotective and one of the compounds responsible for the antidepressant and anxiolytic actions of Rhodiola rosea.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Salidroside decrease expression of hypoxia-inducible factor-1α in cultured human lung cancer cells.
Li, B., et al.
African Journal of Pharmacy and Pharmacology, 34, 2526-2530 (2012)
Marina Perfumi et al.
Phytotherapy research : PTR, 21(1), 37-43 (2006-10-31)
Rhodiola rosea L., or 'golden root', is a popular plant in traditional medicine in Eastern Europe and Asia, with a reputation for improving depression, enhancing work performance, eliminating fatigue and treating symptoms of asthenia subsequent to intense physical and psychological
Li Zhang et al.
Neurochemistry international, 57(5), 547-555 (2010-07-10)
Beta-amyloid (Abeta) peptide, the hallmark of Alzheimer's disease (AD), invokes a cascade of oxidative damages to neurons and eventually leads to neuronal death. In this study, salidroside (Sald), an active compound isolated from a traditional Chinese medicinal plant, Rhodiola rosea
Depeng Li et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 62(1), 9-15 (2012-08-24)
Mastitis is defined as inflammation of the mammary gland in domestic dairy animals and humans. Salidroside, a major component isolated from Rhodiola rosea L., has potent anti-inflammatory properties, but whether it can be used in mastitis treatment has not yet
Erin Wei Qian et al.
Journal of natural products, 75(4), 531-537 (2012-04-10)
Rhodiola rosea is a commonly used folk medicine for the treatment of high altitude sickness, mountain malhypoxia, and anoxia. Its active ingredient, salidroside [2-(4-hydroxyphenyl)ethyl β-D-glucopyranoside (1)], has been reported to have a broad spectrum of biological effects. However, the protective

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