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33981

Supelco

Febantel

VETRANAL®, analytical standard

Synonym(s):

N-{2-[2,3-Bis-(methoxycarbonyl)-guanido]-5-(phenylthio)-phenyl}-2-methoxyacetamide

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About This Item

Empirical Formula (Hill Notation):
C20H22N4O6S
CAS Number:
58306-30-2
Molecular Weight:
446.48
EC Number:
261-205-0
MDL number:
MFCD01738527
UNSPSC Code:
41116107
PubChem Substance ID:
329754720
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

COCC(=O)Nc1cc(Sc2ccccc2)ccc1\N=C(\NC(=O)OC)NC(=O)OC

InChI

1S/C20H22N4O6S/c1-28-12-17(25)21-16-11-14(31-13-7-5-4-6-8-13)9-10-15(16)22-18(23-19(26)29-2)24-20(27)30-3/h4-11H,12H2,1-3H3,(H,21,25)(H2,22,23,24,26,27)

InChI key

HMCCXLBXIJMERM-UHFFFAOYSA-N

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Application

Febantel may be used as a reference standard in the determination of febantel in samples of animal feed and pharmaceutical formulations, using high performance liquid chromatography (HPLC) and high performance liquid chromatography coupled with tandem mass spectrometry (HPLC-MS-MS), respectively.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH6743
BCBW3656
SZBD099XV
SZBA074XV
SZBA074X

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P N Prelezov et al.
DTW. Deutsche tierarztliche Wochenschrift, 110(10), 419-421 (2003-12-04)
Fourteen of 23 dogs developing patent Trichuris vulpis infections by 120 days p.i. with 5000 embryonated eggs were allocated into three groups. One group was treated with flubendazole 220 mg chewable tablets (Flubenol) at the recommended dose regimen once daily
Residues of some veterinary drugs in animals and foods. Joint FAO/WHO Expert Committee on Food Additives.
FAO food and nutrition paper, 41(8), 1-166 (1996-01-01)
Guadalupe Miró et al.
Parasitology research, 100(2), 317-320 (2006-08-18)
Using routine coprological methods, 1161 faecal samples from animal shelters located in Madrid (Spain) were analysed, showing a 28% prevalence for different intestinal parasites: Giardia duodenalis (7%), Cystoisopora spp. (3.8%), Toxocara canis (7.8%), Toxascaris leonina (6.3%), Ancylostomidae (4%), Trichuris vulpis
Efficacy of pyrantel embonate, febantel and praziquantel against Giardia species in naturally infected adult dogs.
A Giangaspero et al.
The Veterinary record, 150(6), 184-186 (2002-03-13)
H Mehlhorn et al.
Parasitology research, 83(5), 419-434 (1997-01-01)
The present study proved that combined administration of pyrantel and febantel to Heterakis spumosa-infected mice yielded clear synergistic effects (seen in a quicker expulsion of the worms and a significant higher degree of worm degeneration), whereas the different doses of
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