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Key Documents

AB136

Sigma-Aldrich

Anti-Dopa Decarboxylase Antibody

Chemicon®, from rabbit

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

canine, sheep, human

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... DDC(1644)

Specificity

DOPA Decarboxylase (DDC). Reacts with a single band of ~55 kDa by Western blot. Reacts best with human samples; reactivity low with rodent and rabbit species.

Immunogen

Synthetic peptide from the N-terminal region of human DDC conjugated to KLH.

Application

Anti-Dopa Decarboxylase Antibody is an antibody against Dopa Decarboxylase for use in WB.
Immunoblotting: 1:1000

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Neuronal & Glial Markers

Physical form

Affinity-purified antibody. Liquid in 10 mM HEPES, pH 7.5, 150 mM NaCl, 100 μg/mL BSA and 50% glycerol.

Storage and Stability

Maintain at -20 to -80°C in undiluted aliquots for up to six months after date of receipt. Store in a non-self-defrosting freezer. Avoid repeated freeze-thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Thamara E Osinga et al.
Neuroendocrinology, 101(4), 289-295 (2015-02-14)
Increased dopamine production may be a feature of head and neck paraganglioma (HNPGL). 18F-fluorodihydroxyphenylalanine positron emission tomography scintigraphy has a high sensitivity for detecting HNPGLs. These observations strongly suggest that HNPGLs have the capacity for L-3,4-dihydroxyphenylalanine uptake and conversion towards
Mohammad M Doroudchi et al.
Journal of neurochemistry, 93(3), 634-640 (2005-04-20)
Although L-DOPA is the drug of choice for Parkinson's disease, prolonged L-DOPA therapy results in decreased drug effectiveness and the appearance of motor complications. This may be due in part to the progressive loss of the enzyme, aromatic L-amino acid
Cerebral infusion of AAV9 vector-encoding non-self proteins can elicit cell-mediated immune responses.
Ciesielska, A; Hadaczek, P; Mittermeyer, G; Zhou, S; Wright, JF; Bankiewicz, KS; Forsayeth, J
Molecular Therapy null
Intrarenal dopamine modulates progressive angiotensin II-mediated renal injury.
Yang, S; Yao, B; Zhou, Y; Yin, H; Zhang, MZ; Harris, RC
American Journal of Physiology: Renal Physiology null
SAFETY AND TOLERABILITY OF MRI-GUIDED INFUSION OF AAV2-hAADC INTO THE MID-BRAIN OF NON-HUMAN PRIMATE.
San Sebastian, W; Kells, AP; Bringas, J; Samaranch, L; Hadaczek, P; Ciesielska et al.
Molecular therapy. Methods & clinical development null

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