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Merck

P-151

Supelco

PEth 16:0/18:1-D5 solution

100 μg/mL in methanol (as free phosphate), certified reference material, ampule of 1 mL, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C39H69D5O8P · NC3H10
Molecular Weight:
767.12
UNSPSC Code:
41116107
NACRES:
NA.24

Pricing and availability is not currently available.

grade

certified reference material

Quality Level

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in methanol (as free phosphate)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

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HPA055244HPA032146SAB4502837
biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

product line

Prestige Antibodies® Powered by Atlas Antibodies

product line

Prestige Antibodies® Powered by Atlas Antibodies

product line

Prestige Antibodies® Powered by Atlas Antibodies

product line

-

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

Gene Information

human ... SP6(80320)

Gene Information

human ... SPN(6693)

Gene Information

human ... SP3(6670)

Gene Information

human ... SP1(6667)

General description

This stable-labeled internal standard is suitable for quantitation of PEth 16:0/18:1 in LC/MS or GC/MS applications. PEth 16:0/18:1, also known as phosphatidylethanol 16:0/18:1, is a sensitive and specific biomarker for alcohol use and abuse. Since the detection window of PEth 16:0/18:1 in blood is longer than that of ethyl glucuronide (EtG) or ethyl sulfate (EtS) in urine, measurement of blood PEth 16:0/18:1 level is routinely performed in clinical toxicology and forensic testing applications such as abstinence monitoring and workplace drug testing. PEth 16:0/18:1 has also been investigated as a biomarker to confirm prenatal alcohol exposure (PAE).

Application


  • Validation of LC-MS/MS method for erythrocyte phosphatidylethanol: A recent study validated a liquid chromatography tandem mass spectrometry method for erythrocyte phosphatidylethanol (PEth), utilizing the PEth 16:0/18:1-D₅ internal standard. This research highlights critical considerations for using PEth as a reliable clinical biomarker of alcohol consumption, proving essential for advancements in biochemical research reagents and methodology (White et al., 2022).


Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup


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