W291102

Piperonal

≥99%, FCC, FG

• Synonym(s): 1,3-Benzodioxole-5-carboxaldehyde, 3,4-(Methylenedioxy)benzaldehyde, Heliotropin
• Empirical Formula (Hill Notation): C₈H₆O₃
• CAS Number: 120-57-0
• Molecular Weight: 150.13
• FEMA Number: 2911
• Beilstein: 131691
• EC Number: 204-409-7
• Council of Europe no.: 104
• MDL number: MFCD00005828
• UNSPSC Code: 12164502
• PubChem Substance ID: 24901389
• Flavis number: 5.016
• NACRES: NA.21

Properties

• biological source: synthetic
• Quality Level: 400
• grade: FG; Fragrance grade; Halal; Kosher
• Agency: follows IFRA guidelines; meets purity specifications of JECFA
• reg. compliance: EU Regulation 1223/2009; EU Regulation 1334/2008 & 178/2002; FCC; FDA 21 CFR 182.60
• vapor pressure: 1 mmHg ( 87 °C)
• Assay: ≥99%
• bp: 264 °C (lit.)
• mp: 35-39 °C (lit.)
• application(s): flavors and fragrances
• Documentation: see Safety & Documentation for available documents
• food allergen: no known allergens
• fragrance allergen: heliotropine
• Organoleptic: cherry; sweet; vanilla
• SMILES string: [H]C(=O)c1ccc2OCOc2c1
• InChI: 1S/C8H6O3/c9-4-6-1-2-7-8(3-6)11-5-10-7/h1-4H,5H2
• InChI key: SATCULPHIDQDRE-UHFFFAOYSA-N

Description

Application

• The synthesis and characterisation of MDMA derived from a catalytic oxidation of material isolated from black pepper reveals potential route specific impurities.: This study explores the synthesis and characterization of MDMA from piperonal, highlighting potential impurities unique to this synthesis route. This research has implications for forensic science and the identification of synthetic routes for MDMA (Plummer et al., 2016).


• Design, synthesis, and biological evaluation of platensimycin analogues with varying degrees of molecular complexity.: This paper details the synthesis of platensimycin analogues using piperonal derivatives. The study evaluates the biological activities of these analogues, contributing to the development of new antibacterial agents (Nicolaou et al., 2008).


• Synthesis and use of 4-peptidylhydrazido-N-hexyl-1,8-naphthalimides as fluorogenic histochemical substrates for dipeptidyl peptidase IV and tripeptidyl peptidase I.: This research presents the synthesis of piperonal-based substrates for histochemical applications, enabling the study of enzyme activities in biochemical assays (Ivanov et al., 2009).

Biochem/physiol Actions

Taste at 10-50 ppm

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H317
• Precautionary Statements: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): 150.1 °F
• Flash Point(C): 65.62 °C
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves