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G7208

Sigma-Aldrich

Ethylene sulfite

98%

Synonym(s):

1,3,2-Dioxathiolan-2-oxide, Cyclic ethylene sulfite, ES, Glycol sulfite

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About This Item

Empirical Formula (Hill Notation):
C2H4O3S
CAS Number:
3741-38-6
Molecular Weight:
108.12
Beilstein:
1237109
EC Number:
223-131-7
MDL number:
MFCD00005354
UNSPSC Code:
12352100
PubChem Substance ID:
24895296
NACRES:
NA.22

Quality Level

200

Assay

98%

form

liquid

refractive index

n20/D 1.445 (lit.)

bp

159.1 °C (lit.)

density

1.426 g/mL at 25 °C (lit.)

SMILES string

O=S1OCCO1

InChI

1S/C2H4O3S/c3-6-4-1-2-5-6/h1-2H2

InChI key

WDXYVJKNSMILOQ-UHFFFAOYSA-N

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

197.1 °F

Flash Point(C)

91.7 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Joseph P O'Shea et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 96, 207-216 (2015-07-29)
Novel formulations that overcome the solubility limitations of poorly water soluble drugs (PWSD) are becoming ever more critical to a drug development process inundated with these compounds. There is a clear need for developing bio-enabling formulation approaches to improve oral
Dharmendra K Yadav et al.
AAPS PharmSciTech, 16(4), 855-864 (2015-01-15)
The objective of this study was to develop novel docetaxel phospholipid nanoparticles (NDPNs) for intravenous administration. Modified solvent diffusion-evaporation method was adopted in the NDPN preparation. Central composite design (CCD) was employed in the optimization of the critical formulation factor
Hywel D Williams et al.
Journal of pharmaceutical sciences, 103(6), 1734-1746 (2014-04-18)
The current study determined the extent to which the desorption of lipid-based formulations (LBFs) from a mesoporous magnesium aluminometasilicate (Neusilin®-US2) carrier is governed by drug properties, LBF composition, and LBF-to-adsorbent ratio. A secondary objective was to evaluate the impact of
Hywel D Williams et al.
Journal of pharmaceutical sciences, 103(8), 2441-2455 (2014-07-06)
The Lipid Formulation Classification System Consortium looks to develop standardized in vitro tests and to generate much-needed performance criteria for lipid-based formulations (LBFs). This article highlights the value of performing a second, more stressful digestion test to identify LBFs near
Mette U Anby et al.
Molecular pharmaceutics, 11(11), 4069-4083 (2014-09-30)
The impact of gastrointestinal (GI) processing and first pass metabolism on danazol oral bioavailability (BA) was evaluated after administration of self-emulsifying drug delivery systems (SEDDS) in the rat. Danazol absolute BA was determined following oral and intraduodenal (ID) administration of
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