Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

760773

Sigma-Aldrich

Dibenzocyclooctyne-PEG4-Fluor 545

for Copper-free Click Chemistry

Synonym(s):

Polyethylene glycol, ADIBO-PEG4-TAMRA, DBCO-PEG4-Fluor 545, DBCO-PEG4-TAMRA, DBCO-PEG4-tetramethylrhodamine, TAMRA DBCO

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C54H57N5O10
Molecular Weight:
936.06
UNSPSC Code:
51171641
NACRES:
NA.22

Quality Level

100

form

solid

reaction suitability

reaction type: click chemistry

storage temp.

−20°C

Related Categories

Application

This azadibenzocyclooctyne-tetramethyl rhodamine (TAMRA) derivative is a versatile fluorescent reagent for labeling azide containing molecules or compounds. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne click chemistry reactions.This dibenzocyclooctyne will react with azide-functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. Subsequent labeled molecules can be visualized by fluorescence spectroscopy.

Spectral Properties: Abs/Em = 545/567nm

related product

Product No.
Description
Pricing

924083

TAMRA-a-TCO

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Accelerated Strain-Promoted and Oxidation-Controlled Cyclooctyne-Quinone Cycloaddition for Cell Labeling.
George A, et al.
ChemistrySelect, 2(24), 7117-7122 null
Rubino F. A., et al.
Journal of Visualized Experiments, 66, 4246-4246 null
Ning, X., et al.
Angewandte Chemie (International Edition in English), 47, 2253-2255 null
Michael D Best
Biochemistry, 48(28), 6571-6584 (2009-06-03)
In recent years, a number of bioorthogonal reactions have been developed, exemplified by click chemistry, that enable the efficient formation of a specific product, even within a highly complex chemical environment. While the exquisite selectivity and reliability of these transformations
Single-step synthesis of small, azide-functionalized gold nanoparticles: Versatile, water-dispersible reagents for click chemistry.
Elliott EW, et al.
Langmuir (2017)
View All Related Papers

Articles

Copper-Free Click Chemistry

Copper-free click chemistry is an alternative approach to click chemistry that proceeds at a lower activation barrier and is free of cytotoxic transition metal catalysts.

Copper-Free Click Chemistry

Copper-free click chemistry is an alternative approach to click chemistry that proceeds at a lower activation barrier and is free of cytotoxic transition metal catalysts.

Copper-Free Click Chemistry

Copper-free click chemistry is an alternative approach to click chemistry that proceeds at a lower activation barrier and is free of cytotoxic transition metal catalysts.

Copper-Free Click Chemistry

Copper-free click chemistry is an alternative approach to click chemistry that proceeds at a lower activation barrier and is free of cytotoxic transition metal catalysts.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service