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747009

Sigma-Aldrich

Poly(styrene)-block-poly(acrylic acid)

PS:PAA 30,000:2,000, PDI ≤1.1

Synonym(s):

PS-PAA, PS-PAA amphiphilic diblock copolymer

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About This Item

Linear Formula:
C4H6N(C8H8)x(C3H4O2)yH
UNSPSC Code:
12352100
NACRES:
NA.23

Quality Level

form

powder

mol wt

Mn 1,000-2,000 (poly(acrylic acid))
Mn 27,000-31,000 (polystyrene)
Mn 28,000-33,000 (total)

PDI

≤1.1

Application

Polystyrene-block-polyacrylic acid is a diblock copolymer used for making polymeric micelles/ vesicles (polymersomes) and other encapsulation applications, . This PS-block-PAA copolymer is 10 wt. % PAA; and should form micelles in water in the 100~200 nm range. The polystyrene degree of polymerization (DP) is 275 and the polyacrylic acid DP is 30.

Legal Information

Sold for research purposes only and subject to field restriction: see www.sigmaaldrich.com/raftlicense. Patents: 7,714,075; 7,250,479; 7,666,962; 6,642,318; 6,747,111; W2010/8356.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Kaoutar Moumile et al.
Journal of clinical microbiology, 42(2), 923-924 (2004-02-10)
We describe a case of primary purulent culture-negative pericarditis caused by Neisseria meningitidis serogroup C occurring in an 8-month-old previously healthy boy, which was detected in pericardial fluid by broad-spectrum PCR amplification.
Dennis E Discher et al.
Science (New York, N.Y.), 297(5583), 967-973 (2002-08-10)
Vesicles are microscopic sacs that enclose a volume with a molecularly thin membrane. The membranes are generally self-directed assemblies of amphiphilic molecules with a dual hydrophilic-hydrophobic character. Biological amphiphiles form vesicles central to cell function and are principally lipids of

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Reversible addition–fragmentation chain transfer (RAFT) polymerization is rapidly moving to the forefront in construction of drug and gene delivery vehicles.

Reversible addition–fragmentation chain transfer (RAFT) polymerization is rapidly moving to the forefront in construction of drug and gene delivery vehicles.

Reversible addition–fragmentation chain transfer (RAFT) polymerization is rapidly moving to the forefront in construction of drug and gene delivery vehicles.

Reversible addition–fragmentation chain transfer (RAFT) polymerization is rapidly moving to the forefront in construction of drug and gene delivery vehicles.

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