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Key Documents

723169

Sigma-Aldrich

Bis[2-(2′-bromoisobutyryloxy)ethyl]disulfide

Synonym(s):

(BiBOE)2S2, ATRP (Bio)degradable Initiator, BiBOEDS

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About This Item

Empirical Formula (Hill Notation):
C12H20Br2O4S2
CAS Number:
Molecular Weight:
452.22
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

form

liquid

Quality Level

refractive index

n20/D 1.529

density

1.478 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

CC(C)(Br)C(=O)OCCSSCCOC(=O)C(C)(C)Br

InChI

1S/C12H20Br2O4S2/c1-11(2,13)9(15)17-5-7-19-20-8-6-18-10(16)12(3,4)14/h5-8H2,1-4H3

InChI key

PXBWWYBXPGZCHC-UHFFFAOYSA-N

Application

Atom Transfer Radical Polymerisation (ATRP) initiator for the preparation of biodegradable polymers as well as polymers that adhere to gold surfaces. May also be used to introduce a temperature and light sensitive cleavable region into the polymer.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Tsarevsky, N.V.; Matyjaszewski, K.
Macromolecules, 35, 9009-9009 (2002)
Hao Zhao et al.
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Highly efficient nanoarchitectures are of great interest for achieving precise chemotherapy with minimized adverse side effects in cancer therapy. However, a major challenge remains in exploring a rational approach to synthesize spatiotemporally selective vehicles for precise cancer chemotherapy. Here, we
Wenjing Huang et al.
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Reversing multidrug resistance (MDR) remains a big challenge in cancer therapy. Combining the hyperthermia and chemotherapy is a promising strategy for efficient cancer treatment with MDR reversal. Gold nanocages (GNCs) are an ideal photothermal (PTT)-chemotherapy integration platform due to their

Articles

ATRP is a successful method for precise polymer synthesis with controlled molecular weights and high chain end functionalities.

ATRP is a successful method for precise polymer synthesis with controlled molecular weights and high chain end functionalities.

ATRP is a successful method for precise polymer synthesis with controlled molecular weights and high chain end functionalities.

ATRP is a successful method for precise polymer synthesis with controlled molecular weights and high chain end functionalities.

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Protocols

Polymerization via ATRP procedures demonstrated by Prof. Dave Haddleton's research group at the University of Warwick.

Polymerization via ATRP procedures demonstrated by Prof. Dave Haddleton's research group at the University of Warwick.

Polymerization via ATRP procedures demonstrated by Prof. Dave Haddleton's research group at the University of Warwick.

Polymerization via ATRP procedures demonstrated by Prof. Dave Haddleton's research group at the University of Warwick.

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