702412

N-Boc-trans-4-fluoro-L-proline methyl ester

97%

• Synonym(s): 1-tert-Butyl 2-methyl (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate
• Empirical Formula (Hill Notation): C₁₁H₁₈FNO₄
• CAS Number: 203866-18-6
• Molecular Weight: 247.26
• MDL number: MFCD07367993
• UNSPSC Code: 12352005
• PubChem Substance ID: 329762373
• NACRES: NA.22

Properties

• Assay: 97%
• form: powder
• optical activity: [α]22/D -80.0°, c = 1 in methanol
• mp: 34-39 °C
• functional group: ester; fluoro
• storage temp.: 2-8°C
• SMILES string: COC(=O)[C@@H]1C[C@@H](F)CN1C(=O)OC(C)(C)C
• InChI: 1S/C11H18FNO4/c1-11(2,3)17-10(15)13-6-7(12)5-8(13)9(14)16-4/h7-8H,5-6H2,1-4H3/t7-,8+/m1/s1
• InChI key: METPQQHVRNLTRX-SFYZADRCSA-N

Description

Application

N-Boc-trans-4-fluoro-L-proline methyl ester can be used as a substrate in the preparation of pyrrolidinine-thioxotetrahydropyrimidinone based catalysts, which find application in asymmetric organic reactions.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): >230.0 °F
• Flash Point(C): > 110 °C
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves