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551295

Sigma-Aldrich

N-Cyclopropyl-2,4,6-triamino-1,3,5-triazine

97%

Synonym(s):

N-Cyclopropyl-1,3,5-triazin-2,4,6-triamine, Cyromazin

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About This Item

Empirical Formula (Hill Notation):
C6H10N6
CAS Number:
66215-27-8
Molecular Weight:
166.18
Beilstein:
882879
EC Number:
266-257-8
MDL number:
MFCD00078650
UNSPSC Code:
12352100
PubChem Substance ID:
24879213
NACRES:
NA.22

Quality Level

100

Assay

97%

mp

223-227 °C (lit.)

SMILES string

Nc1nc(N)nc(NC2CC2)n1

InChI

1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)

InChI key

LVQDKIWDGQRHTE-UHFFFAOYSA-N

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General description

N-Cyclopropyl-2,4,6-triamino-1,3,5-triazine, also known as cyromazine, is an insect growth regulator(IGR) that is commonly used as an insecticide. It undergoes metabolism in plants and animals to form melamine. Surface-enhanced Raman scattering (SERS) spectroscopic study indicates that it interacts with the surface of silver colloid through the lone pair on nitrogen.

Pictograms

Environment
GHS09

Hazard Statements

H411

Precautionary Statements

P273 - P391 - P501

Hazard Classifications

Aquatic Chronic 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

212.0 °F - closed cup

Flash Point(C)

100 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Raman and surface-enhanced Raman study of insecticide cyromazine.
Mukherjee K, et al.
Vibrational Spectroscopy, 25(1), 91-99 (2001)
Hongyuan Yan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 908, 137-142 (2012-10-09)
A simple, convenient and high selective molecularly imprinted matrix solid-phase dispersion (MI-MSPD) using water-compatible cyromazine-imprinted polymer as adsorbent was proposed for the rapid screening of melamine from bovine milk coupled with liquid chromatography-ultraviolet detection. The molecularly imprinted polymers (MIPs) synthesized
Xinle Zhu et al.
Journal of agricultural and food chemistry, 57(23), 11075-11080 (2009-11-11)
A gas chromatography-mass spectrometric (GC-MS) method was established for the determination of cyromazine and its metabolite, melamine, in animal-derived food. Chicken and tilapia muscle samples were spiked with (15)N(3)-melamine, extracted with an acidic acetonitrile/water solution, and defatted with dichloromethane. Egg
Scott Ferguson et al.
Journal of economic entomology, 103(6), 2197-2203 (2011-02-12)
In this study, random amplified polymorphic DNA polymerase chain reaction (RAPD-PCR) was used to identify polymorphic genomic DNA that would discriminate among cyromazine-resistant, abamectin-resistant, and susceptible Liriomyza trifolii (Burgess) (Diptera: Agromyzidae) leafminers. Using a reference strain that was susceptible to
Xianhua Wang et al.
Journal of separation science, 35(12), 1432-1438 (2012-06-29)
The combination of molecularly imprinted polymer with high performance liquid chromatography has been developed to determine cyromazine and its metabolic melamine in some samples. However, the potential risk of template leakage used in molecularly imprinted polymer is a major disadvantage.
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