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363073

Sigma-Aldrich

Poly(vinyl alcohol)

average Mw 31,000-50,000, 87-89% hydrolyzed

Synonym(s):

PVA

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About This Item

Linear Formula:
[-CH2CHOH-]n
CAS Number:
9002-89-5
MDL number:
MFCD00081922
UNSPSC Code:
12352104
NACRES:
NA.23
Pricing and availability is not currently available.

Quality Level

200

form

crystalline powder
crystals or granules
powder

mol wt

average Mw 31,000-50,000

falling ball

5.2-6.2 cP, 4 % in H2O(20 °C)(lit.)

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI key

IMROMDMJAWUWLK-UHFFFAOYSA-N

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General description

Poly(vinyl alcohol) (PVA) is a vinyl based water soluble polymer that can be used as a non-ionic surface active agent. It can also be used as a biodegradable polymer and can be incorporated in adhesives, coatings, textiles ceramics and cosmetics. Its properties include good transparency, chemical resistance, toughness and anti-electrostatic properties.[1][2][3]

Application

PVA can be used in the preparation of microspheres which can be further used as biodegradable microcarriers.[4][5][6]

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

No data available

Flash Point(C)

No data available

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW5222
MKCS5217
MKCR2252
MKCQ1863
MKCN6182

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Compostable Polymer Properties and Packaging Applications
Plastic Films in Food Packaging, 217-248 (2013)
Gas foamed open porous biodegradable polymeric microspheres
Kim TK, et al.
Biomaterials, 27(2), 152-159 (2006)
Poly (D, L lactic-co-glycolic acid) microspheres as biodegradable microcarriers for pluripotent stem cells
Newman KD and McBurney MW
Biomaterials, 25(26), 5763-5771 (2004)
PLGA/alginate composite microspheres for hydrophilic protein delivery
Zhai P, et al.
Materials Science and Engineering, C, 56(26), 251-259 (2015)
Elisa Rojas-Prats et al.
Pharmaceutics, 13(2) (2021-02-03)
A potent cell division cycle 7 (CDC7) kinase inhibitor, known as PHA-767491, has been described to reduce the transactive response DNA binding protein of 43 KDa (TDP-43) phosphorylation in vitro and in vivo, which is one of the main proteins
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Questions

1–2 of 2 Questions  

  1. Once dissolved, does the powder get separated from the solution? If so, how long does it take to be separated from solvent (assuming that solvent is water)?

    1 answer

    1. This product is water soluble up to 20%. The material is expected to stay in solution with proper preparation and storage. General instructions are as follows:
      1. Use unheated water
      2. Add water to vessel and initiate agitation or stirring
      3. Add desired amount of PVA, gradually, up to 20%
      4. Heat solution while stirring to 85°C, hold for 30 minutes

      To maintain the product in solution, do not store at temperatures lower that 15°C.
      Solutions stored at temperatures higher than 24°C should include a biocidal agent.

      Helpful?

  2. Is there information available regarding the solubility of product 363073, which is a PVA (poly vinyl alcohol)? Additionally, how can this particular product be dissolved?

    1 answer

    1. The solubility of product 363073, PVA (poly vinyl alcohol), indicates that it should dissolve in heated water, DMSO, and glycerol. It is expected to be around 40-50mg/mL soluble in hot water at a temperature of approximately 90-95 degrees Celsius.

      Helpful?

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