337056

4-(Trifluoromethoxy)aniline

98%

• Synonym(s): α,α,α-Trifluoro-p-anisidine
• Linear Formula: CF₃OC₆H₄NH₂
• CAS Number: 461-82-5
• Molecular Weight: 177.12
• Beilstein: 2090209
• EC Number: 207-317-5
• MDL number: MFCD00041314
• UNSPSC Code: 12352100
• PubChem Substance ID: 24860453
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 98%
• form: liquid
• refractive index: n20/D 1.463 (lit.)
• bp: 73-75 °C/10 mmHg (lit.)
• density: 1.32 g/mL at 20 °C (lit.)
• SMILES string: Nc1ccc(OC(F)(F)F)cc1
• InChI: 1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2
• InChI key: XUJFOSLZQITUOI-UHFFFAOYSA-N

Description

Application

4-(Trifluoromethoxy)aniline was used in the synthesis of:

• side-group liquid-crystalline polymethacrylates with fluorine-containing mesogens
• derivatives of 3-(quinolin-3-yl)acrylates
• series of novel Shiff bases, via condensation with pyridinecarboxaldehydes in the presence of molecular sieves

Safety Information

• Pictograms: GHS06,GHS08,GHS05
• Signal Word: Danger
• Hazard Statements: H301,H310,H315,H318,H373
• Precautionary Statements: P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P305 + P351 + P338 + P310 - P314
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 3 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT RE 2
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 2
• Flash Point(F): 177.8 °F - closed cup
• Flash Point(C): 81 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves