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07076

Sigma-Aldrich

Castor Oil, Hydrogenated,Ethoxylated

Synonym(s):

Cremophor® RH 40, Macrogolglycerol hydroxystearate, PEG-40 castor oil, Polyoxyl 40 hydrogenated castor oil, RH 40

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About This Item

CAS Number:
61788-85-0
MDL number:
MFCD01771439
UNSPSC Code:
12161900
NACRES:
NA.25

impurities

≤0.2% sulfated ash (verfied on random samples only)
≤1 ppm ethylene oxide
≤10 ppm dioxan
≤10 ppm heavy metals (verfied on random samples only)
≤2 ppm arsenic (verfied on random samples only)
≤2.0% water
≤5000 ppm acetic acid
≤620 ppm diethylene glycol
≤620 ppm ethylene glycol

ign. residue

≤0.25% (verfied onrandom samples only)

acid value

≤0.8 mg KOH/g

hydroxyl value

60‑75 mg KOH/g

iodine value

≤1.0 g I2/100 g

saponification value

50‑60 mg KOH/g

suitability

suitable for acidity or alkalinity

Related Categories

Application

Castor Oil, Hydrogenated,Ethoxylated is used to solubilize vitamins, water insoluble active substances and essential oils in water or mixtures of water and alcohol.

Other Notes

Castor Oil, Hydrogenated, Ethoxylated is the brand name for a range of non-ionic polyethoxylated detergents. It was developed for use as solubilizers and emulsifiers.

Analysis Note

congealing temperature 16-26°C

Legal Information

Cremophor is a registered trademark of BASF SE

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

467.6 °F

Flash Point(C)

242 °C

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Christofori M R R Nastiti et al.
Pharmaceutics, 12(2) (2020-02-06)
Resveratrol (RSV) is a potent lipophilic antioxidant with a low aqueous solubility. Novel nanoformulations have been successfully developed and evaluated to increase the potential of resveratrol as a skin targeting antioxidant. Nanoformulations were prepared using a spontaneous emulsification method, and
Allergic contact dermatitis to polyethylene glycol-7 hydrogenated castor oil.
M Kalavala et al.
Contact dermatitis, 56(5), 287-288 (2007-04-20)
William J Gradishar et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 23(31), 7794-7803 (2005-09-21)
ABI-007, the first biologically interactive albumin-bound paclitaxel in a nanameter particle, free of solvents, was compared with polyethylated castor oil-based standard paclitaxel in patients with metastatic breast cancer (MBC). This phase III study was performed to confirm preclinical studies demonstrating
Kouichi Nakagawa
Lipids, 42(5), 457-462 (2007-05-04)
Head group behavior of nonionic amphiphilic compound, (poly(oxyethylene) hydrogenated castor oil, HCO), in aqueous dispersions were investigated by EPR (electron paramagnetic resonance) in conjunction with a modern slow-tumbling simulation. The aliphatic spin probes, 5-doxylstearic acid (5-DSA) and 3beta-doxyl-5alpha-cholestane (CHL), were
Enas A Mahmoud et al.
AAPS PharmSciTech, 10(1), 183-192 (2009-02-25)
The purpose of this study was to combine the advantages of self-nanoemulsifying drug delivery systems and tablets as a conventional dosage form emphasizing the excipients' effect on the development of a new dosage form. Systems composed of HCO-40, Transcutol HP
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