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SCR027

Sigma-Aldrich

Rat Mesenchymal Stem Cells (Bone Marrow)

These primary bone marrow derived Rat Mesenchymal Stem Cells isolated from the iliac crest of adult Fisher 344 rats provide a convenient source of multipotent rat mesenchymal stem cells.

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About This Item

UNSPSC Code:
41106509
eCl@ss:
32011203
NACRES:
NA.81

biological source

rat

Quality Level

100

manufacturer/tradename

Chemicon®

technique(s)

cell culture | stem cell: suitable

input

sample type mesenchymal stem cell(s)

shipped in

liquid nitrogen

General description

Mesenchymal stem cells, also known as marrow stromal cells, are defined as a self-renewing population of adherent, bone-marrow-derived multipotent progenitor cells with the capacity to differentiate into several mesenchymal cell lineages. In defined in vitro assays, mesenchymal stem cells have been shown to readily differentiate into lineage-specific cells that form bone, cartilage, fat, tendon, and muscle tissues. Mesenchymal stem cells also provide support and maintenance for the other major stem cell population in the bone marrow, the hematopoietic stem cells.

Cell Line Description

Mesenchymal Stem Cells

Application

Research Category
Stem Cell Research
These primary bone marrow derived Rat Mesenchymal Stem Cells isolated from the iliac crest of adult Fisher 344 rats provide a convenient source of multipotent rat mesenchymal stem cells.

Components

1x10e6 viable Rat Mesenchymal Stem Cells derived from the bone marrow of adult Fisher 344 rats.

Quality

- Each vial contains at least 1x10e6 viable cells at passage 2.
- Cells are derived from certified pathogen-free Fisher 344 rats.
- Cells tested negative for mycoplasma contamination.
- Cells tested positive for CD90 expression; negative for CD45 and CD31 expression.

Storage and Stability

Rat Mesenchymal Stem Cells (Bone Marrow) should be stored in liquid nitrogen. The cells can be passaged for at least 3-5 additional passages.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Antonella Rocca et al.
International journal of nanomedicine, 10, 433-445 (2015-01-23)
Enhancement of the osteogenic potential of mesenchymal stem cells (MSCs) is highly desirable in the field of bone regeneration. This paper proposes a new approach for the improvement of osteogenesis combining hypergravity with osteoinductive nanoparticles (NPs). In this study, we
Alicia Jurado et al.
Frontiers in pharmacology, 13, 1081345-1081345 (2023-01-31)
Background: Patients with obstructive sleep apnea (OSA) experience recurrent hypoxemic events with a frequency sometimes exceeding 60 events/h. These episodic events induce downstream transient hypoxia in the parenchymal tissue of all organs, thereby eliciting the pathological consequences of OSA. Whereas
Margaret F Bennewitz et al.
Molecular imaging and biology, 14(6), 676-687 (2012-03-16)
Glioblastoma multiforme (GBM) is a lethal disease marked by infiltration of cancerous cells into the surrounding normal brain. The dire outcome of GBM patients stems in part from the limitations of current neuroimaging methods. Notably, early cancer detection methodologies are
Gokhan Burcin Kubat et al.
Journal of biochemical and molecular toxicology, 35(1), e22612-e22612 (2020-09-02)
The effect of dysfunctional mitochondria in several cell pathologies has been reported in renal diseases, including diabetic nephropathy and acute kidney injury. Previous studies have reported that mitochondrial transplantation provided surprising results in myocardial and liver ischemia, as well as

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Highly characterized human mesenchymal stem cell lines from bone-marrow, adipose and umbilical cord along with serum-free MSC expansion and differentiation media.

Mesenchymal Stem Cell Culture

Highly characterized human mesenchymal stem cell lines from bone-marrow, adipose and umbilical cord along with serum-free MSC expansion and differentiation media.

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