P2C100C05

Pellicon^® 2 Cassette Ultrafiltration Module

filtration area 0.5 m², NMWCO 100 kDa

• Synonym(s): Pellicon 2 Cassette Ultrafiltration Module PLCHK C 0.5 m²
• UNSPSC Code: 23151806

Properties

• material: composite regenerated cellulose (CRC) ; polypropylene screen; polyurethane adhesive
• Quality Level: 400
• manufacturer/tradename: Pellicon^®
• parameter: 0.33 bar max. transmembrane pressure (5 psig) (reverse); 3.5 bar max. transmembrane pressure (50 psig) at 30 °C (forward); 5-35 L/min recirculation rate at 0.4 bar (6 psi)
• technique(s): analytical sample preparation: suitable; protein purification: suitable
• H: 1.5 cm (0.6 in.)
• L: 21 cm (8.3 in.)
• W: 17.8 cm (7.0 in.)
• filtration area: 0.5 m²
• membrane nominal area: 0.5 m²
• gravimetric extractables: ≤1500 mg/m²
• matrix: Ultracel^®
• pore size: 100 kDa NMWCO
• pH: 2-13

Description

General description

The Pellicon^® 2 Ultrafiltration PLCHK Cassette sets the standard in cassette-style tangential flow filtration devices. P2C100C05 was designed with process scale-up and applications development in mind.

Millipore′s PLCHK polyethersulfone membrane has void-free structures that guard against leakage of solutes through microdefects normally associated with voids beneath the thin skins of conventional UF membranes. These void-free membranes are more permeable, resulting in high-flux with equivalent or superior product retention. These void-free membranes provide the advantages of fast, high yield processing and smaller systems.

The Pellicon^® 2 Cassette Ultrafiltration Module feature a filtration area of 0.5 m² with a pore size of 100 kDa NMWCO.

Application

Concentration, desalting or buffer exchange of:

• Protein solutions
• Polysaccharide solutions
• Virus suspensions

Harvest, washing or clarification of:

• Cell cultures and lysates
• Colloidal suspensions
• Viral cultures

Features and Benefits

• Type C screen (coarse screen)
• Leading-edge void- free membranes to match virtually any separation challenge
• Short flow path for higher flux and higher resolution separation capability
• Choice of flow channel configuration providing process optimization capability
• Predictable, fast, scale-up
• True linear scalability from laboratory size modules to industrial assemblies for processing thousands of liters
• Brings higher resolution, improved yields and superior back-pressure resistance
• Ultracel membranes are composite membranes cast on a microporous substrate for defect-free membranes with superior

Other Notes

These products are manufactured in a facility which adheres to FDA Good Manufacturing Practices.

Prefiltration Rquirements: 100 µm

Analysis Note

Gravimetric Extractables: after a water flush

Legal Information

Pellicon is a registered trademark of Merck KGaA, Darmstadt, Germany

ULTRACEL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2