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939684

Sigma-Aldrich

Poly(glycerol succinate)

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Synonym(s):

PGSu

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About This Item

Linear Formula:
[CH2CH(OH)CH2OOC(CH2)2COO]n
UNSPSC Code:
12162002

form

paste

Quality Level

100

color

white

General description

Poly(glycerol succinate) (PGSu) is a biodegradable polymer synthesized from two bio-based monomers: glycerol and succinic acid. It is a new green hyperbranched polyester (HBPEs) with tunable mechanical properites, potentially useful in soft tissue engineering and regenerative medicine applications. The polymer backbone and crosslinks can undergo hydrolytic degradation due to the presence of ester linkages. The ester bonds in the polymer backbone covalently crosslink to form a three-dimensional (3D) network of random coils at higher temperature (>130 °C) under vacuum without using any toxic crosslinkers.

Application

  • Suitable as plasticizer
  • In the drug delivery systems
  • Tissue engineering and regenerative medicine
  • Medical device development

Features and Benefits

*Tunable mechanical properties

*Higher reversible deformations property

*Bioresorbable polymer

*Accelerant for degrading non degradable polymers

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW3022

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Poly(Glycerol Succinate) as an Eco-Friendly Component of PLLA and PLCL Fibres towards Medical Applications
Kolbuk D, et. al.
Polymers, 12(8), 1731-1731 (2020)
Colloids and Surfaces A: Physicochemical and Engineering Aspects
Agach, et. al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 419, 263-267 (2013)

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