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G004716

HPLC Analysis of Ketoconazole Enantiomers on Astec® CYCLOBOND I 2000 HP-RSP

application for HPLC

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technique(s)

HPLC: suitable

test parameters

column: CYCLOBOND I 2000 HP-RSP, 25 cm x 4.6 mm I.D., 5 μm particles (24024AST)
mobile phase: [A] 0.1% formic acid; [B] acetonitrile; (70:30, A:B)
flow rate: 1 mL/min
column temp.: 25 °C
injection: 1 μL
detector: UV, 230 nm
sample: 1 mg/mL in methanol

suitability

application for HPLC

application(s)

pharmaceutical (small molecule)

Legal Information

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany

Analyte

Description

    Ketoconazole, 99.0-101.0% (EP, titration)

standard

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Description
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