Skip to Content
Merck
All Photos(2)

Documents

N4779

Sigma-Aldrich

5-Nitro-2-(3-phenylpropylamino)benzoic acid

≥98%

Synonym(s):

NPPB

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C16H16N2O4
CAS Number:
107254-86-4
Molecular Weight:
300.31
MDL number:
MFCD00153851
UNSPSC Code:
12352200
PubChem Substance ID:
24277859
NACRES:
NA.77

Assay

≥98%

form

solid

solubility

ethanol: 3 mg/mL
DMSO: 37 mg/mL
H2O: insoluble

storage temp.

−20°C

SMILES string

OC(=O)c1cc(ccc1NCCCc2ccccc2)[N+]([O-])=O

InChI

1S/C16H16N2O4/c19-16(20)14-11-13(18(21)22)8-9-15(14)17-10-4-7-12-5-2-1-3-6-12/h1-3,5-6,8-9,11,17H,4,7,10H2,(H,19,20)

InChI key

WBSMIPAMAXNXFS-UHFFFAOYSA-N

Biochem/physiol Actions

Potent chloride channel blocker.

Features and Benefits

This compound is featured on the Chloride Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Tae Sik Sung et al.
The Journal of physiology, 596(9), 1549-1574 (2018-02-13)
Enteric neurotransmission is essential for gastrointestinal (GI) motility, although the cells and conductances responsible for post-junctional responses are controversial. The calcium-activated chloride conductance (CaCC), anoctamin-1 (Ano1), was expressed by intramuscular interstitial cells of Cajal (ICC-IM) in proximal stomach and not
Alwin Scharstuhl et al.
PloS one, 4(8), e6688-e6688 (2009-08-21)
We previously identified curcumin as a potent inducer of fibroblast apoptosis, which could be used to treat hypertrophic scar formation. Here we investigated the underlying mechanism of this process. Curcumin-induced apoptosis could not be blocked by caspase-inhibitors and we could
Valia Verrière et al.
PloS one, 7(5), e37746-e37746 (2012-06-05)
Cystic Fibrosis (CF) is a genetic disease characterised by a deficit in epithelial Cl(-) secretion which in the lung leads to airway dehydration and a reduced Airway Surface Liquid (ASL) height. The endogenous lipoxin LXA(4) is a member of the
Michael R Bristow et al.
JACC. Basic to translational science, 5(9), 871-883 (2020-08-25)
Using serial analysis of myocardial gene expression employing endomyocardial biopsy starting material in a dilated cardiomyopathy cohort, we show that mRNA expression of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) cardiac myocyte receptor ACE2 is up-regulated with remodeling and with reverse
Agnieszka Dyrda et al.
PloS one, 5(2), e9447-e9447 (2010-03-03)
The mechanical, rheological and shape properties of red blood cells are determined by their cortical cytoskeleton, evolutionarily optimized to provide the dynamic deformability required for flow through capillaries much narrower than the cell's diameter. The shear stress induced by such
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service