T-093

Delta⁹-Tetrahydrocannabinolic acid A solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Synonym(s): THCA-A
• Empirical Formula (Hill Notation): C₂₂H₃₀O₄
• CAS Number: 23978-85-0
• Molecular Weight: 358.47
• MDL number: MFCD20133805
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material
• Quality Level: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 1.0 mg/mL in acetonitrile
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): cannabis testing; cannabis testing
• format: single component solution
• shipped in: dry ice
• storage temp.: −70°C
• SMILES string: OC1=C(C(O)=O)C(CCCCC)=CC2=C1[C@H](C=C(C)CC3)[C@@H]3C(C)(C)O2
• InChI: 1S/C22H30O4/c1-5-6-7-8-14-12-17-19(20(23)18(14)21(24)25)15-11-13(2)9-10-16(15)22(3,4)26-17/h11-12,15-16,23H,5-10H2,1-4H3,(H,24,25)/t15-,16-/m1/s1
• InChI key: UCONUSSAWGCZMV-HZPDHXFCSA-N

Description

General description

This certified Snap-N-Spike^® solution is suitable for THCA-A testing methods by GC/MS, LC/MS or HPLC for applications in clinical toxicology, testing of cannabis potency or impurity profiling, pharmaceutical research, forensic analysis, and urine drug testing. Cerilliant solution Certified Reference Materials (CRMs) of cannabinoids are supplied in a convenient, quantitative, US DEA-exempt solution format and with TK#s for Canadian customers.

Δ9-Tetrahydrocannabinolic acid A (THCA-A) is a non-psychoactive acidic cannabinoid found in Cannabis that reportedly exhibits anti-inflammatory, neuroprotective, and anti-cancer effects. It is also the precursor to the main psychoactive cannabinoid found in cannabis, called Δ-9-tetrahydrocannabinol (Δ-9-THC).

Application

The Certified Reference Material (CRM) in solution can also be used as follows:

• Gas chromatographic-mass spectrometric (GC-MS) analysis of ten main cannabinoids from hemp inflorescences following their silylation and esterification for derivatization
• Development and validation of an HPLC-DAD method for the simultaneous analysis of five major neutral and acidic cannabinoids in cannabis and hashish samples
• Multi-analysis of 11 cannabinoids in biomass and extracts of different cannabis varieties by an HPLC-UV method, following the International Conference on Harmonization (ICH) Tripartite Guideline for Validation of Analytical Procedures
• Analysis of hemp seed oil samples for identification and estimation of seven major cannabinoids by HPLC coupled to a UV detector
• Estimation of ∆9-tetrahydrocannabinolic acid in blood and plasma samples using liquid chromatography-tandem mass spectrometry (LC-MS/MS)
• Simultaneous analysis of ∆9-tetrahydrocannabinol, ∆9-tetrahydrocannabinolic acid-A, cannabidiol, and cannabinol by an HPLC-DAD method in confiscated cannabis products

Features and Benefits

• Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
• Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
• Rigorously tested through real-time stability studies to ensure accuracy and shelf life
• Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
• Flame sealed under argon into ampoules for long-term shelf life
• Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H302 + H312 + H332,H319
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 35.6 °F - closed cup
• Flash Point(C): 2.0 °C - closed cup