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W348708

Sigma-Aldrich

Ethyl maltol

≥99%, FCC, FG

Synonym(s):

2-Ethyl-3-hydroxy-4H-pyran-4-one, Ethyl maltol

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About This Item

Empirical Formula (Hill Notation):
C7H8O3
CAS Number:
4940-11-8
Molecular Weight:
140.14
FEMA Number:
3487
EC Number:
225-582-5
Council of Europe no.:
692
MDL number:
MFCD00059795
UNSPSC Code:
12164502
PubChem Substance ID:
24901730
Flavis number:
7.047
NACRES:
NA.21

biological source

synthetic

Quality Level

400

grade

FG
Fragrance grade
Halal
Kosher

Agency

follows IFRA guidelines

reg. compliance

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FCC
FDA 21 CFR 172.515

Assay

≥99%

mp

85-95 °C (lit.)

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

fragrance allergen

no known allergens

Organoleptic

caramel; sweet

SMILES string

CCC1=C(O)C(=O)C=CO1

InChI

1S/C7H8O3/c1-2-6-7(9)5(8)3-4-10-6/h3-4,9H,2H2,1H3

InChI key

YIKYNHJUKRTCJL-UHFFFAOYSA-N

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Application


  • Flavoring Agents in E-cigarette Liquids: A Comprehensive Analysis of Multiple Health Risks.: Analyzes health risks associated with various flavoring agents, including ethyl maltol, in e-cigarette liquids, providing critical insights into their potential biochemical interactions and toxicological profiles (Sachdeva et al., 2023).

  • Effect of lactic acid bacteria co-fermentation on antioxidant activity and metabolomic profiles of a juice made from wolfberry and longan.: Explores the impact of lactic acid bacteria co-fermentation on beverages containing ethyl maltol, focusing on changes in antioxidant activity and metabolomic profiles which are crucial for understanding its biochemical effects (Zheng et al., 2023).

  • Adverse Biophysical Impact of e-Cigarette Flavors on Pulmonary Surfactant.: Investigates the negative effects of e-cigarette flavors, including ethyl maltol, on pulmonary surfactant, highlighting the biochemical implications of inhaling flavored vapors (Goros et al., 2023).

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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R C Hider et al.
Biochemical pharmacology, 39(6), 1005-1012 (1990-03-15)
The ability of a number of heterocyclic metal chelators to deliver zinc into red cells, to release the liganded zinc to haemoglobin and thereby cause a left shift in the oxygen dissociation curve of intact red cells has been investigated.
J A Levey et al.
Biochemical pharmacology, 37(10), 2051-2057 (1988-05-15)
Accumulation of radioactive iron (59Fe) into isolated fragments of rat small intestine in the presence of two hydroxypyrones, maltol and ethyl maltol, was compared with that in the presence of another chelator of iron(III), nitrilotriacetic acid (NTA). The characteristics of
A el-Jammal et al.
Journal of chromatography. B, Biomedical applications, 658(1), 121-127 (1994-08-05)
The pursuit of orally available Fe(III) chelating agents has resulted in several clinical trials of 1,2-dimethyl-3-hydroxypyrid-4-one (CP20). Chromatography of this and related Fe chelators on silica-based columns has proven difficult due to unwanted interactions with the stationary phase, including with
Yuanyuan Yue et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 96, 316-323 (2012-06-19)
This paper was designed to investigate the interaction of ethyl maltol with human serum albumin (HSA) under physiological condition by fluorescence, synchronous fluorescence, three-dimensional fluorescence, Fourier transformation infrared spectra, and molecular docking method. Spectroscopic analysis of the emission quenching at
F Schved et al.
Letters in applied microbiology, 22(3), 189-191 (1996-03-01)
When used separately, 20 mmol l-1 maltol or 1600 AU ml-1 nisin resulted in a 0-0.6 log10 reduction in viable counts of Escherichia coli in a buffer system. However, when added in combination they yielded a 1.8-5.5-log-cycle reduction in viable
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