73035AST

Astec^® CHIRALDEX^™ G-TA Capillary GC Column

L × I.D. 50 m × 0.25 mm, d_f 0.12 μm

• Synonyme(s) : GC column, chiral, gamma-dextran
• Code UNSPSC : 41115710
• Nomenclature NACRES : SB.54

Propriétés

• Matériaux: fused silica
• Niveau de qualité: 100
• Description: GC capillary column
• Conditionnement: pkg of 1 ea
• Paramètres: -10-180 °C temperature (isothermal or programmed)
• Valeur bêta: 500
• df: 0.12 μm
• Technique(s): gas chromatography (GC): suitable
• L × D.I.: 50 m × 0.25 mm
• Groupe de la matrice active: non-bonded; 2,6-di-O-pentyl-3-trifluoroacetyl derivative of γ-cyclodextrin phase
• Application(s): agriculture; chemicals and industrial polymers; cleaning products; clinical; cosmetics; environmental; flavors and fragrances; food and beverages; forensics and toxicology; life science and biopharma; personal care; pharmaceutical (small molecule)
• Type de colonne: capillary chiral
• Technique de séparation: chiral

Description

Description générale

Astec^® CHIRALDEX G-TA is the first choice in the Group 1 CSPs (Surface Interactions, Complex Derivatives). This phase has been shown to be the most broadly-selective phase for the pharmaceutical industry, especially for the analysis of chiral intermediates and drug studies in various stages of clinical trials. Separations occur without the inclusion mechanism and are typically faster and more efficient than most chiral stationary phases. G-TA has also been used to separate parent drug enantiomers and their metabolites. G-TA has its highest selectivity for oxygen-containing analytes like alcohols, diols and polyols as the free alcohol and as an acyl derivative; amines as acyl derivatives; amino alcohols, halogens (Cl>Br>F), amino acids, hydroxy acids, lactones, furans and pyrans. It is also highly selective for halogenated compounds.

Application

• Enantioselective gas chromatographic analysis of aqueous samples by on-line derivatisation. Application to enzymatic reactions.: This study explores the use of the Astec CHIRALDEX G-TA Capillary GC Column for enantioselective gas chromatographic analysis. The method involves on-line derivatization, enabling the analysis of aqueous samples and applying this technique to enzymatic reactions. This innovative approach highlights the column′s capability in achieving high selectivity and sensitivity for chiral compounds in complex matrices (Mommers et al., 2008).

Résistance chim./phys.

Temp. Limits:

• -10 °C to 180 °C isothermal and programmed

Autres remarques

We offer a variety of chromatography accessories including analytical syringes

Informations légales

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany

CHIRALDEX is a trademark of Sigma-Aldrich Co. LLC