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Key Documents

T3705

Sigma-Aldrich

Transferrin human

Optiferrin™, recombinant, expressed in rice

Synonyme(s) :

Optiferrin™

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About This Item

Numéro CAS:
11096-37-0
Numéro CE :
234-318-8
Numéro MDL:
MFCD00132442
Code UNSPSC :
12352202
Nomenclature NACRES :
NA.61

Source biologique

human

Niveau de qualité

200

Produit recombinant

expressed in rice

Pureté

≥95% (agarose gel electrophoresis)

Forme

powder

Composition

Protein, ≥90%

Teneur en fer

≥300 μg/g

Technique(s)

immunoprecipitation (IP): suitable
tissue culture: suitable

Impuretés

≤1.0 EU/mg Endotoxin

Numéro d'accès UniProt

P02787

Température de stockage

−20°C

Informations sur le gène

human ... TF(7018)

Description générale

Transferrin is an 80 kDa serum glycoprotein, which is expressed in hepatocytes. The gene is located on human chromosome 3q22.1.
Optiferrin™ is recombinant human transferrin that is completelyblood-free. Optiferrin’s performance is equivalent to human holo transferrin incell culture and offers significant regulatory advantages due to its safety andconsistency. Optiferrin is suitable for a broad range of cell types thatinclude stem, primary, and bioproduction cells.

Application

Transferrin Human has been used to perform immunoprecipitation measurements. It has also been used for the preparation of essential 8 medium.

Actions biochimiques/physiologiques

Human transferrin was shown to promote allogeneic chimerism in mice after irradiation and transplantation of incompatible bone marrow.
Transferrin facilitates the transfer of iron to erythron and peripheral tissues. It stimulates the proliferation of human lymphocytes. Mutations in this gene are linked to atransferrinemia.

Autres remarques

1). Patent Rights
U.S. Patent No. 9,321,828
2). Registered Trademark Rights
U.S. Reg. 3,880,881
International Reg. 1,466,509

Informations légales

Optiferrin is a trademark of InVitria

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Effect of transferrin, lactoferrin and chelated iron on human T-lymphocytes
Djeha A and Brock JH
British Journal of Haematology, 80(2), 235-241 (1992)
TFRC (transferrin receptor (p90, CD71))
Dorak MT
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2009)
Chemically defined culture and cardiomyocyte differentiation of human pluripotent stem cells
Burridge PW, et al.
Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et al.], 87(1), 21-23 (2015)
Derivation of highly purified cardiomyocytes from human induced pluripotent stem cells using small molecule-modulated differentiation and subsequent glucose starvation
Sharma A, et al.
Journal of Visualized Experiments, (97) (2015)
E Axelman et al.
Thrombosis and haemostasis, 112(3), 466-477 (2014-07-18)
Heparanase is implicated in cell invasion, tumour metastasis and angiogenesis. It forms a complex and enhances the activity of the blood coagulation initiator - tissue factor (TF). We describe new peptides derived from the solvent accessible surface of TF pathway
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