SML1236

(−)-Nicotine hydrogen tartrate salt

≥98% (HPLC)

• Synonyme(s) : (−)-Nicotine ditartrate, (−)-1-Methyl-2-(3-pyridyl)pyrrolidine (+)-bitartrate salt
• Formule empirique (notation de Hill): C₁₀H₁₄N₂ · 2C₄H₆O₆
• Numéro CAS: 65-31-6
• Poids moléculaire : 462.41
• Numéro CE : 200-607-2
• Code UNSPSC : 12352210
• ID de substance PubChem : 329825736
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: ≥98% (HPLC)
• Forme: powder
• Activité optique: [α]/D +20 to +26°, c = 1.0 in water
• Conditions de stockage: desiccated
• Couleur: white to beige
• Solubilité: H₂O: 20 mg/mL, clear
• Température de stockage: room temp
• Chaîne SMILES: CN1CCC[C@H]1C2=CC=CN=C2.C
• InChI: 1S/C10H14N2.CH4/c1-12-7-3-5-10(12)9-4-2-6-11-8-9;/h2,4,6,8,10H,3,5,7H2,1H3;1H4/t10-;/m0./s1
• Clé InChI: RYYKFQGHMYGLEL-PPHPATTJSA-N

Description

Application

(−)-Nicotine hydrogen tartrate salt has been used as an agonist for acetylcholine receptor (AChr).

(−)-Nicotine hydrogen tartrate salt has been used in intracellular calcium imaging.

Actions biochimiques/physiologiques

NHT is considered to be more stable than nicotine. Nicotine is highly addictive drug and is indirectly but strongly associated with tobacco related diseases. It helps to discontinue smoking. Nicotine might serve as a therapeutic agent in treating Alzheimer’s disease, Parkinson’s disease and ulcerative colitis.

Prototype nicotinic acetylcholine receptor agonist; naturally occurring isomer.

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08,GHS09
• Mention d'avertissement: Danger
• Mentions de danger: H301,H319,H330,H361d,H411
• Conseils de prudence: P202 - P260 - P264 - P273 - P304 + P340 + P310 - P305 + P351 + P338
• Classification des risques: Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2
• Code de la classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 289.8 °F
• Point d'éclair (°C): 143.2 °C