Accéder au contenu
Merck
Toutes les photos(1)

Key Documents

SCP0020

Sigma-Aldrich

[Sar1]-Angiotensin II

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(1)

About This Item

Formule empirique (notation de Hill):
C49H71N13O10
Poids moléculaire :
1002.17
Code UNSPSC :
12352209
Nomenclature NACRES :
NA.32

Pureté

≥95% (HPLC)

Forme

lyophilized

Composition

Peptide Content, ≥65%

Conditions de stockage

protect from light

Température de stockage

−20°C

Amino Acid Sequence

Sar-Arg-Val-Tyr-Ile-His-Pro-Phe

Application

Angiotensins are peptide hormone components of the renin-angiotensin system involved in the regulation of blood vessel constriction and aldosterone release. Angiotensin I, a decapeptide derived from angiotensinogen, is a converted to Angiotensin II by the removal of the two C-terminal amino acids. Various analogues of Angiotensins I and II made by amino acid substitution are used in structure and sequence studies to analyze and differentiate the functions of natural angiotensins.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Novel concept in the mechanism of injury and protection of gastric mucosa: role of Renin-Angiotensin system and active metabolites of Angiotensin.
Brzozowski T, Ptak-Belowska A, et al.
Current Medicinal Chemistry, 16, 55-62 (2012)
Kar Neng Lai et al.
Contributions to nephrology, 170, 135-144 (2011-06-11)
Diabetic nephropathy (DN) is a leading cause of end-stage renal disease in developed countries where type 2 diabetes mellitus has reached epidemic proportions. Although the exact pathogenesis of DN is not fully understood and is likely diverse in nature, there
Vani X Oliveira et al.
Regulatory peptides, 172(1-3), 1-7 (2011-07-27)
Angiotensin II (AII) is the active octapeptide product of the renin enzymatic cascade, which is responsible for sustaining blood pressure. In an attempt to establish the AII-receptor-bound conformation of this octapeptide, we designed conformationally constrained analogues by scanning the entire
Mauricio Sendeski et al.
Radiology, 251(3), 697-704 (2009-04-16)
To determine whether a type of contrast medium (CM), iodixanol, modifies outer medullary descending vasa recta (DVR) vasoreactivity and nitric oxide (NO) production in isolated microperfused DVR. Animal handling conformed to the Animal Care Committee Guidelines of all participating institutions.

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique