SBR00094

Valnemulin hydrochloride

≥96% (HPLC), powder

• Synonyme(s) : Econor
• Formule empirique (notation de Hill): C₃₁H₅₂N₂O₅S · HCl
• Numéro CAS: 133868-46-9
• Poids moléculaire : 601.28
• Numéro MDL: MFCD08458958
• Code UNSPSC : 51101500

Propriétés

• Niveau de qualité: 100
• Pureté: ≥96% (HPLC)
• Forme: powder
• Spectre d'activité de l'antibiotique: Gram-negative bacteria; Gram-positive bacteria
• Mode d’action: protein synthesis | inhibits
• Conditions d'expédition: ambient
• Température de stockage: −20°C
• Chaîne SMILES: CC(C)[C@@H](N)C(NCC(C)(C)SCC(O[C@H]1[C@](C)([C@@H]2C)[C@@]3([H])[C@@](CC2)(CCC3=O)[C@@H](C)[C@H](O)[C@](C)(C=C)C1)=O)=O.Cl
• InChI: 1S/C31H52N2O5S.ClH/c1-10-29(8)15-22(38-23(35)16-39-28(6,7)17-33-27(37)24(32)18(2)3)30(9)19(4)11-13-31(20(5)26(29)36)14-12-21(34)25(30)31;/h10,18-20,22,24-26,36H,1,11-17,32H2,2-9H3,(H,33,37);1H/t19-,20+,22-,24-,25+,26+,29-,30+,31+;/m1./s1
• Clé InChI: MFBPRQKHDIVLOJ-AFFLPQGKSA-N

Description

Description générale

Valnemulin Hydrochloride is an antibiotic which belongs to the class of compounds known as pleuromutilins. It is a semisynthetic derivative of the naturally occurring antibiotic tiamulin. Valnemulin Hydrochloride has activity against various Gram-positive and some Gram-negative bacteria, including Mycoplasma and some anaerobic bacteria, as well as the protozoan parasite Eimeria.

Actions biochimiques/physiologiques

Valnemulin Hydrochloride inhibits bacterial protein synthesis by binding to the 50S subunit of the bacterial ribosome. More specifically, it binds to the peptidyl transferase center of the ribosome and interferes with the transfer of amino acids to growing polypeptide chains, leading to the inhibition of protein synthesis and bacterial death.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302
• Conseils de prudence: P264 - P270 - P301 + P312 - P501
• Classification des risques: Acute Tox. 4 Oral
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable