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S3147

5-Sulfosalicylic acid dihydrate

Name: 5-Sulfosalicylic acid dihydrate
Brand: SIGMA

suitable for electrophoresis, ≥99%

Synonyme(s) :

2-Hydroxy-5-sulfobenzoic acid

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A propos de cet article

Formule linéaire :

HO₃SC₆H₃-2-(OH)CO₂H·2H₂O

Numéro CAS:

5965-83-3

Poids moléculaire :

254.21

UNSPSC Code:

41105319

NACRES:

NB.22

PubChem Substance ID:

24899547

EC Number:

202-555-6

Beilstein/REAXYS Number:

650741

MDL number:

MFCD00149540

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Propriétés

Quality Segment

200

assay

≥99%

form

powder or crystals

technique(s)

electrophoresis: suitable

impurities

≤0.02% Insoluble matter, ≤0.05% Salicylic Acid

mp

105-110 °C (lit.)

solubility

water: soluble 100 mg/mL, clear, colorless

anion traces

chloride (Cl^-): ≤0.001%, sulfate (SO₄^2-): ≤0.035%

cation traces

Fe: ≤0.001%, heavy metals (as Pb): ≤0.002%

SMILES string

[H]O[H].[H]O[H].OC(=O)c1cc(ccc1O)S(O)(=O)=O

InChI

1S/C7H6O6S.2H2O/c8-6-2-1-4(14(11,12)13)3-5(6)7(9)10;;/h1-3,8H,(H,9,10)(H,11,12,13);2*1H2

InChI key

BHDKTFQBRFWJKR-UHFFFAOYSA-N

Description

General description

5-Sulfosalicylic acid is a strong acid capable of protonating water. It forms a new theophylline complex, which was investigated by X-ray photoelectron spectroscopy (XPS). It forms 1:1 proton-transfer compounds with the ortho-substituted monocyclic heteroaromatic Lewis bases. Their crystal structures have been studied.

Application

5-Sulfosalicylic acid dihydrate may be employed for the quantification of doxorubicin derived from PEGylated liposomal doxorubicin (Doxil) and its major metabolite in human plasma by HPLC. It may be used in the preparation of poly[[tris(di-2-pyridylamine)tris([μ]-5-sulfonatosalicylato)tricopper(II)] trihydrate].

5-Sulfosalicylic acid (3.5%) in 12% trichloroacetic acid is commonly used as a fixing solution for proteins in agarose and polyacrylamide gels.