MAK014
Glucose-6-Phosphate Assay Kit
sufficient for 100 colorimetric tests
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About This Item
Code UNSPSC :
12161503
Nomenclature NACRES :
NA.84
Produits recommandés
Utilisation
sufficient for 100 colorimetric tests
Méthode de détection
colorimetric
Maladie(s) pertinente(s)
hematological disorder
Température de stockage
−20°C
Description générale
Glucose 6-phosphate (G6P) is a key metabolic intermediate that enters either metabolic pathways or storage. G6P is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P lies at the beginning of both glycolysis and the pentose phosphate pathways. It also can be stored as glycogen when blood glucose levels are high.
Application
Glucose-6-phosphate assay kit has been used in:
- glucose 6-phosphate (G6P) assay
- quantification of glucose-6-phosphate (G6P) and fructose-6-phosphate (F6P)
- metabolite analysis
Adéquation
Suitable for quantifying Glucose-6-Phosphate in a variety of samples.
Principe
G6P is utilized by Glucose-6-phosphate dehydrogenase to generate reducing equivalents in the form of NADPH. This is particularly important in red blood cells where a G6PDH deficiency leads to hemolytic anemia. G6P is determined by an enzyme assay, which results in a colorimetric (450 nm) product, proportional to the G6P present. Typical sensitivities of detection are between 1-30 nmoles.
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Description
Tarif
Mention d'avertissement
Danger
Mentions de danger
Classification des risques
Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B
Code de la classe de stockage
8A - Combustible corrosive hazardous materials
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