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L5125

Sigma-Aldrich

N-Lauroylsarcosine sodium salt

≥94%

Synonyme(s) :

N-Dodecanoyl-N-methylglycine sodium salt, Sarkosyl NL

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About This Item

Formule linéaire :
CH3(CH2)10CON(CH3)CH2COONa
Numéro CAS:
137-16-6
Poids moléculaire :
293.38
Numéro Beilstein :
5322974
Numéro CE :
205-281-5
Numéro MDL:
MFCD00042728
Code UNSPSC :
12352107
ID de substance PubChem :
57654330
Nomenclature NACRES :
NA.32

Description

anionic

Niveau de qualité

200

Pureté

≥94%

Forme

powder

Poids mol.

micellar avg mol wt 600
average mol wt 600

Nombre d'agrégation

2

Technique(s)

oligo synthesis: suitable

CMC

14.6 mM (20-25°C)

Solubilité

H2O: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow

Chaîne SMILES 

[Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O

InChI

1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1

Clé InChI

KSAVQLQVUXSOCR-UHFFFAOYSA-M

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Catégories apparentées

Application

N-Lauroylsarcosine sodium salt has been used as one of the components of the lysing solution in the cornet assay. It has been used for lysing protoplasts in the process of chromosomal DNA isolation form Streptococcus mutans.

Actions biochimiques/physiologiques

N-Lauroylsarcosine is an anionic surfactant which also has protein denaturant potency. In addition, it has been shown as a microbicide for sexually transmitted diseases.

Autres remarques

Anionic surfactant.

Pictogrammes

Skull and crossbonesCorrosion
GHS06,GHS05

Mention d'avertissement

Danger

Mentions de danger

H315,H318,H330

Classification des risques

Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2

Code de la classe de stockage

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de danger pour l'eau (WGK)

WGK 1

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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P W Caufield et al.
Journal of clinical microbiology, 27(2), 274-278 (1989-02-01)
Attempts to study the acquisition, transmission, and other aspects of the natural history of Streptococcus mutans infections in humans have been hampered by limitations and inconsistencies in methods by which phenotypic characteristics of individual isolates are examined. Because most mutans
N S Andrade et al.
Genetics and molecular research : GMR, 7(4), 1414-1421 (2009-02-19)
Baccharis dracunculifolia De Candole (DC) (Asteraceae) is indigenous throughout southeastern Latin America and is used by local people in traditional medicine. This plant is known to be the source of resin for the highly valued Brazilian green propolis. As no
Sarah Houben et al.
Frontiers in molecular neuroscience, 13, 106-106 (2020-08-09)
Alzheimer's disease (AD) is characterized by the accumulation in the brain of intraneuronal aggregates of abnormally and hyperphosphorylated tau proteins and of extracellular deposits of amyloid-β surrounded by dystrophic neurites. Numerous experimental models have shown that tau pathology develops in
Royford Bundi Magiri et al.
Vaccines, 8(2) (2020-05-24)
Vaccination is the most efficient method of protection against influenza infections. However, the rapidly mutating viruses and development of new strains make it necessary to develop new influenza vaccines annually. Hence, vaccines that stimulate cross-protection against multiple influenza subtypes are
Kunie Ando et al.
Acta neuropathologica, 139(4), 773-789 (2020-01-12)
Genome-wide association studies (GWAS) have identified PICALM as one of the most significant susceptibility loci for late-onset Alzheimer's disease (AD) after APOE and BIN1. PICALM is a clathrin-adaptor protein and plays critical roles in clathrin-mediated endocytosis and in autophagy. PICALM
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