L1645
Anti-Human Lambda Light Chain (Bound and Free) antibody produced in goat
affinity isolated antibody, buffered aqueous solution
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About This Item
Produits recommandés
Source biologique
goat
Niveau de qualité
Conjugué
unconjugated
Forme d'anticorps
affinity isolated antibody
Type de produit anticorps
secondary antibodies
Clone
polyclonal
Forme
buffered aqueous solution
Technique(s)
indirect ELISA: 1:2,500
Conditions d'expédition
dry ice
Température de stockage
−20°C
Modification post-traductionnelle de la cible
unmodified
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Description générale
Immunoglobulins (Ig) are produced by the B cells and play crucial role in host humoral immune response. A typical immunoglobulin consists of two heavy chains and two light chains. The two light chains are either κ or the λ chain. The B cells express one type of light chain during their life time.
Lambda (λ) light chain comprises an amino-terminal variable region and carboxy-terminal constant region. λ chain is biologically critical and constitutes up to 30 to 40% of human immunoglobulin (Ig) molecules. The human λ locus is mapped to the chromosome location 22.
Application
Anti-Human Lambda Light Chain (Bound and Free) antibody has been used in surface plasmon resonance assay.
Anti-Human Lambda Light Chain (bound and free) antibody produced in goat has been used in indirect enzyme linked immuno sorbent assay (ELISA).
Forme physique
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as preservative
Stockage et stabilité
For continuous use, store at 2-8 °C for up to one month.For extended storage, solution may be frozen inworking aliquots. Repeated freezing and thawing is notrecommended. Storage in "frost-free" freezers is notrecommended.If slight turbidity occurs upon prolonged storage, clarify by centrifugation before use.
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
nwg
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Structural and functional properties of human lambda-light-chain variable-region subgroups.
A Solomon et al.
Clinical and diagnostic laboratory immunology, 2(4), 387-394 (1995-07-01)
B-cell development
Hematology (2018)
Adam W Clarke et al.
mAbs, 10(4), 664-677 (2018-02-14)
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Jinhao Bi et al.
Emerging microbes & infections, 12(1), 2149351-2149351 (2022-12-02)
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Advaita Acarya Singh et al.
Scientific reports, 10(1), 6201-6201 (2020-04-12)
Broadly neutralising antibodies (bNAbs) against human immunodeficiency virus type 1 (HIV-1), such as CAP256-VRC26 are being developed for HIV prevention and treatment. These Abs carry a unique but crucial post-translational modification (PTM), namely O-sulfated tyrosine in the heavy chain complementarity
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