H8017

Hydroxocobalamin acetate

vitamin B₁₂ analog

• Synonyme(s) : Vitamin B_12a acetate
• Formule empirique (notation de Hill): C₆₄H₉₁CoN₁₃O₁₆P
• Numéro CAS: 22465-48-1
• Poids moléculaire : 1388.39
• Numéro CE : 245-019-7
• Numéro MDL: MFCD00082532
• Code UNSPSC : 12352205
• eCl@ss : 34058004
• ID de substance PubChem : 329815248
• Nomenclature NACRES : NA.79

Propriétés

• Source biologique: synthetic (organic)
• Niveau de qualité: 200
• Pureté: ≥95% (HPLC)
• Forme: powder
• Technique(s): HPLC: suitable
• Couleur: red to brown
• Température de stockage: 2-8°C
• Chaîne SMILES: CC(CNC(=O)CC[C@]1(C)[C@@H](CC(N)=O)[C@H]2N=C1C(C)=C3N=C(C=C4N=C(C(C)=C5[C@@H](CCC(N)=O)[C@](C)(CC(N)=O)[C@@]2(C)N5[Co]OC(C)=O)[C@@](C)(CC(N)=O)[C@@H]4CCC(N)=O)C(C)(C)[C@@H]3CCC(N)=O)OP([O-])(=O)O[C@H]6[C@@H](O)[C@H](O[C@@H]6CO)n7cnc8cc(C)c(C)cc78
• InChI: 1S/C62H90N13O14P.C2H4O2.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2(3)4;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H3,(H,3,4);/q;;+2/p-3/t31?,34-,35-,36-,37+,41-,52-,53-,56-,57+,59-,60+,61+,62+;;/m1../s1
• Clé InChI: QHSPIHUMLGFPKX-WYVZQNDMSA-K

Description

Description générale

Hydroxocobalamin is an analog of vitamin B₁₂ with OH as an alkyl group. Vitamin B₁₂ cobalamin refers to a group of chemically-related cobalt containing molecules.

Actions biochimiques/physiologiques

Vitamin B₁₂ cobalamin is involved in DNA synthesis and fatty acid synthesis. It also plays a vital role as a coenzyme in the conversion of mitochondrial methylmalonyl co-enzyme A to succinyl co-enzyme A. Vitamin B₁₂ cobalamin is also involved in neurotransmitter synthesis and erythropoiesis. It also functions in the synthesis and maintenance of myelin sheath. Hydroxocobalamin (vitamin B_12a, OHCbl) and cyanocobalamin (CNCbl) are storage and delivery forms.

Informations sur la sécurité

• Pictogrammes: GHS08
• Mention d'avertissement: Warning
• Mentions de danger: H351
• Conseils de prudence: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Classification des risques: Carc. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable