Accéder au contenu
Merck
Toutes les photos(2)

Key Documents

View All Documentation

G5417

SAFC

Glycine

Fabrication pharma

Synonyme(s) :

Acide aminoacétique, Acide aminoéthanoïque, Glycocolle

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(2)

About This Item

Formule linéaire :
NH2CH2COOH
Numéro CAS:
56-40-6
Poids moléculaire :
75.07
Numéro Beilstein :
635782
Numéro CE :
200-272-2
Numéro MDL:
MFCD00008131
Code UNSPSC :
12352209
eCl@ss :
32160406
Nomenclature NACRES :
NA.25

Source biologique

non-animal source

Niveau de qualité

400

Pureté

≥98.5%

Forme

crystalline powder

Technique(s)

cell culture | mammalian: suitable

Impuretés

endotoxin, heavy metals, trace metals, residual solvents, tested

pH

5.9-6.4

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

Pf

240 °C (dec.) (lit.)

Solubilité

H2O: 100 mg/mL

Absorption UV

λ: 260 nm Amax: ≤0.04
λ: 260 nm Amax: -0.006
λ: 280 nm Amax: ≤0.04
λ: 280 nm Amax: -0.003

Adéquation

suitable for manufacturing use

Application(s)

pharmaceutical (small molecule)

Activité étrangère

cytotoxicity, tested

Chaîne SMILES 

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

Clé InChI

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Informations sur le gène

rat ... Grin2a(24409)

Vous recherchez des produits similaires ? Visite Guide de comparaison des produits

Description générale

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
To request the documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.

Application

Glycine is a non-essential amino acid. It is the simplest of the amino acids and plays various roles in biology. It is structurally unique among the biological amino acids in that it does not have an asymmetric center, and thus is not chiral. It is commonly used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Actions biochimiques/physiologiques

Neurotransmetteur inhibiteur de la moelle épinière, régulateur allostérique des récepteurs du NMDA.

Informations légales

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Code de la classe de stockage

13 - Non Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Les clients ont également consulté

Slide 1 of 7

1 of 7

Glycine tested according to Ph. Eur.

Sigma-Aldrich

50058

Glycine

Sigma-Aldrich

Sigma-Aldrich

67419

Glycine 1 M solution

Glycine BioXtra, ≥99% (titration)

Sigma-Aldrich

G7403

Glycine

Glycine puriss. p.a., reag. Ph. Eur., buffer substance, 99.7-101% (calc. to the dried substance)

Sigma-Aldrich

33226

Glycine

Glycine Cytiva 17-1323-01, pack of 500 g

GE17-1323-01

Glycine

Glycine crystalline, EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP

SAFC

1.00590

Glycine

Glycine 99%, FCC

Sigma-Aldrich

W328707

Glycine

Alexander Carvajal-González et al.
Brain : a journal of neurology, 137(Pt 8), 2178-2192 (2014-06-22)
The clinical associations of glycine receptor antibodies have not yet been described fully. We identified prospectively 52 antibody-positive patients and collated their clinical features, investigations and immunotherapy responses. Serum glycine receptor antibody endpoint titres ranged from 1:20 to 1:60 000.
Zoé Husson et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(28), 9418-9431 (2014-07-11)
The principal neurons of the cerebellar nuclei (CN), the sole output of the olivo-cerebellar system, receive a massive inhibitory input from Purkinje cells (PCs) of the cerebellar cortex. Morphological evidence suggests that CN principal cells are also contacted by inhibitory
Bethany L Johnson-Kerner et al.
Human molecular genetics, 24(5), 1420-1431 (2014-11-16)
Giant axonal neuropathy (GAN) is a progressive neurodegenerative disease caused by autosomal recessive mutations in the GAN gene resulting in a loss of a ubiquitously expressed protein, gigaxonin. Gene replacement therapy is a promising strategy for treatment of the disease;
Dmitrij A Lisak et al.
Biochimica et biophysica acta, 1853(9), 2104-2114 (2015-03-15)
Bax inhibitor-1 (BI-1) is an evolutionarily conserved pH-dependent Ca²⁺ leak channel in the endoplasmic reticulum and the founding member of a family of six highly hydrophobic mammalian proteins named transmembrane BAX inhibitor motif containing (TMBIM) 1-6 with BI-1 being TMBIM6.
Rosalie Fisher et al.
Genome biology, 15(8), 433-433 (2014-08-28)
Genomic analysis of multi-focal renal cell carcinomas from an individual with a germline VHL mutation offers a unique opportunity to study tumor evolution. We perform whole exome sequencing on four clear cell renal cell carcinomas removed from both kidneys of
Afficher tous les articles scientifiques apparentés

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique