E6758

Ethylenediaminetetraacetic acid

anhydrous, crystalline, BioReagent, suitable for cell culture

• Synonyme(s) : (Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid
• Formule linéaire : (HO₂CCH₂)₂NCH₂CH₂N(CH₂CO₂H)₂
• Numéro CAS: 60-00-4
• Poids moléculaire : 292.24
• Numéro Beilstein : 1716295
• Numéro CE : 200-449-4
• Numéro MDL: MFCD00003541
• Code UNSPSC : 12161700
• eCl@ss : 39030907
• ID de substance PubChem : 24894634
• Nomenclature NACRES : NA.25

Propriétés

• Qualité: anhydrous
• Niveau de qualité: 200
• Gamme de produits: BioReagent
• Pureté: ≥98.5%
• Forme: crystalline
• Pertinence de la réaction: reagent type: chelator
• Technique(s): cell culture | mammalian: suitable
• pH: 2.5 (23 °C, 10 g/L)
• Pf: 250 °C (dec.) (lit.)
• Solubilité: 3 M NaOH: 100 mg/mL
• Densité: 1.46 g/cm³ at 20 °C
• Traces de cations: C: 40.7-41.5%; N: 9.3-9.8%
• Chaîne SMILES: OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O
• InChI: 1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)
• Clé InChI: KCXVZYZYPLLWCC-UHFFFAOYSA-N

Description

Application

Ethylenediaminetetraacetic acid has been used:

• as a component of peptide dilution buffer for intracellular BH3 (Bcl-2 homology (BH) domain) profiling and validation
• as a medium component in the hepatic stellate cell (HSCs) culture
• as a component of homogenization buffer for protein extraction from eye tissues
• for stopping benzonase reaction in lysis buffer

Actions biochimiques/physiologiques

Ethylenediaminetetraacetic acid (EDTA) is an anticoagulant, majorly used in preventing clotting of blood samples. EDTA may trigger aggregation of platelets resulting in pseudothrombocytopenia. EDTA along with tetracycline imparts serves as root conditioning agent and provides relief in gum infection. EDTA-tetracycline therapy decreases coronary artery calcium levels in atherosclerosis. Calcium Disodium EDTA administration is effective in slowing down the progression of chronic kidney disease.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H319
• Conseils de prudence: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Classification des risques: Eye Irrit. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves